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  • Project/Pilot Project Leaders

    Christina R. Bourne

    • Johnson BP, Kumar V, Scull EM, Thomas LM, Bourne CR, Singh S. Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus. ACS Chem Biol. 2022 Jan 21;17(1):85-102. doi: 10.1021/acschembio.1c00655. Epub 2021 Dec 14. PMID: 34905349.
    • Snead KJ, Moore LL, Bourne CR. ParD Antitoxin Hotspot Alters a Disorder-to-Order Transition upon Binding to Its Cognate ParE Toxin, Lessening Its Interaction Affinity and Increasing Its Protease Degradation Kinetics. Biochemistry. 2022 Jan 4;61(1):34-45. doi: 10.1021/acs.biochem.1c00584. Epub 2021 Dec 16. PMID: 34914378.

    Anthony Burgett

    • Subramaniyan B, Larabee JL, Bodas M, Moore AR, Burgett AWG, Myers DA, Georgescu C, Wren JD, Papin JF, Walters MS. Characterization of the SARS-CoV-2 Host Response in Primary Human Airway Epithelial Cells from Aged Individuals. Viruses. 2021 Aug 12;13(8):1603. doi: 10.3390/v13081603. PMID: 34452468; PMCID: PMC8402710.

    Rudragouda Channappanavar

    • Antony F, Pundkar C, Sandey M, Jaiswal AK, Mishra A, Kumar A, Channappanavar R, Suryawanshi A. IFN-λ Regulates Neutrophil Biology to Suppress Inflammation in Herpes Simplex Virus-1-Induced Corneal Immunopathology. J Immunol. 2021 Apr 15;206(8):1866-1877. doi: 10.4049/jimmunol.2000979. PMID: 33811102.

    Yong Cheng

    • Schorey JS, Cheng Y, McManus WR. Bacteria- and host-derived extracellular vesicles - two sides of the same coin? J Cell Sci. 2021 Jun 1;134(11):jcs256628. doi: 10.1242/jcs.256628. Epub 2021 Jun 3. PMID: 34081134; PMCID: PMC8214758.

    Michael Scott Davis

    • Davis MS. Glucocentric Metabolism in Ultra-Endurance Sled Dogs. Integr Comp Biol. 2021 Jul 23;61(1):103-109. doi: 10.1093/icb/icab026. PMID: 33871632.
    • Davis MS, Barrett MR. Effect of conditioning and physiological hyperthermia on canine skeletal muscle mitochondrial oxygen consumption. J Appl Physiol (1985). 2021 May 1;130(5):1317-1325. doi: 10.1152/japplphysiol.00969.2020. Epub 2021 Mar 4. PMID: 33661725.
    • von Pfeil DJF, Davis MS, Liska WD, George C, Secrest S. Orthopedic and ultrasonographic examination findings in 128 shoulders of 64 ultra-endurance Alaskan sled dogs. Vet Surg. 2021 May;50(4):794-806. doi: 10.1111/vsu.13621. Epub 2021 Mar 8. PMID: 33684250.
    • Tosi I, Art T, Boemer F, Votion DM, Davis MS. Acylcarnitine profile in Alaskan sled dogs during submaximal multiday exercise points out metabolic flexibility and liver role in energy metabolism. PLoS One. 2021 Aug 12;16(8):e0256009. doi: 10.1371/journal.pone.0256009. PMID: 34383825; PMCID: PMC8360531.

    Junpeng Deng

    • Mishra SJ, Khandelwal A, Banerjee M, Balch M, Peng S, Davis RE, Merfeld T, Munthali V, Deng J, Matts RL, Blagg BSJ. Selective Inhibition of the Hsp90α Isoform. Angew Chem Int Ed Engl. 2021 May 3;60(19):10547-10551. doi: 10.1002/anie.202015422. Epub 2021 Mar 26. PMID: 33621416; PMCID: PMC8086817.
    • Jia H, Xue S, Lei L, Fan M, Peng S, Li T, Nagarajan R, Carver B, Ma Z, Deng J, Yan L. A semi-dominant NLR allele causes whole-seedling necrosis in wheat. Plant Physiol. 2021 May 27;186(1):483-496. doi: 10.1093/plphys/kiab058. PMID: 33576803; PMCID: PMC8154059.
    • Pathak PK, Zhang F, Peng S, Niu L, Chaturvedi J, Elliott J, Xiang Y, Tadege M, Deng J. Structure of the unique tetrameric STENOFOLIA homeodomain bound with target promoter DNA. Acta Crystallogr D Struct Biol. 2021 Aug 1;77(Pt 8):1050-1063. doi: 10.1107/S205979832100632X. Epub 2021 Jul 29. PMID: 34342278; PMCID: PMC8329861.
    • Peng S, Meng X, Zhang F, Pathak PK, Chaturvedi J, Coronado J, Morales M, Mao Y, Qian SB, Deng J, Xiang Y. Structure and function of an effector domain in antiviral factors and tumor suppressors SAMD9 and SAMD9L. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2116550119. doi: 10.1073/pnas.2116550119. PMID: 35046037; PMCID: PMC8795524.

    Yu Feng

    • Zhao J, Feng Y, Tian G, Taylor C, Arden NS. Influences of puff protocols and upper airway anatomy on cannabis pharmacokinetics: A CFPD-PK study. Comput Biol Med. 2021 May;132:104333. doi: 10.1016/j.compbiomed.2021.104333. Epub 2021 Mar 13. PMID: 33770654.
    • Hayati H, Feng Y, Hinsdale M. Inter-species Variabilities of Droplet Transport, Size Change, and Deposition in Human and Rat Respiratory Systems: An In Silico J Aerosol Sci. 2021 May;154:105761. doi: 10.1016/j.jaerosci.2021.105761. Epub 2021 Jan 23. PMID: 33776134; PMCID: PMC7990120.
    • Yi H, Feng Y, Gappa-Fahlenkamp H. Analysis of topical dosing and administration effects on ocular drug delivery in a human eyeball model using computational fluid dynamics. Comput Biol Med. 2022 Feb;141:105016. doi: 10.1016/j.compbiomed.2021.105016. Epub 2021 Nov 3. PMID: 34782111.
    • Li B, Feng Y. In Silico Study to Enhance Delivery Efficiency of Charged Nanoscale Nasal Spray Aerosols to the Olfactory Region Using External Magnetic Fields. Bioengineering (Basel). 2022 Jan 16;9(1):40. doi: 10.3390/bioengineering9010040. PMID: 35049749; PMCID: PMC8773240.

    Heather Gappa-Fahlenkamp

    • Yi H, Feng Y, Gappa-Fahlenkamp H. Analysis of topical dosing and administration effects on ocular drug delivery in a human eyeball model using computational fluid dynamics. Comput Biol Med. 2022 Feb;141:105016. doi: 10.1016/j.compbiomed.2021.105016. Epub 2021 Nov 3. PMID: 34782111.

    Wouter Hoff

    • Truitt C, Hoff WD, Deole R. Health Functionalities of Betaine in Patients With Homocystinuria. Front Nutr. 2021 Sep 9;8:690359. doi: 10.3389/fnut.2021.690359. PMID: 34568401; PMCID: PMC8459993.
    • Mix LT, Hara M, Fuzell J, Kumauchi M, Kaledhonkar S, Xie A, Hoff WD, Larsen DS. Not All Photoactive Yellow Proteins Are Built Alike: Surprises and Insights into Chromophore Photoisomerization, Protonation, and Thermal Reisomerization of the Photoactive Yellow Protein Isolated from Salinibacter ruber. J Am Chem Soc. 2021 Nov 24;143(46):19614-19628. doi: 10.1021/jacs.1c08910. Epub 2021 Nov 15. PMID: 34780163.

    Erika Lutter

    • Adhikari S, Essandoh MA, Starr WC, Sah P, La Force CN, Eleshy RG, Lutter EI, Nelson TL. Eumelanin-Inspired Antimicrobial with Biocidal Activity against Methicillin-Resistant Staphylococcus aureus. ACS Appl Bio Mater. 2022 Feb 21;5(2):545-551. doi: 10.1021/acsabm.1c01036. Epub 2022 Feb 3. PMID: 35113537.

    Laura-Isobel McCall

    • Liu Z, Ulrich vonBargen R, McCall LI. Central role of metabolism in Trypanosoma cruzi tropism and Chagas disease pathogenesis. Curr Opin Microbiol. 2021 Oct;63:204-209. doi: 10.1016/j.mib.2021.07.015. Epub 2021 Aug 26. PMID: 34455304; PMCID: PMC8463485.
    • Parab AR, McCall LI. Tryp-ing Up Metabolism: Role of Metabolic Adaptations in Kinetoplastid Disease Pathogenesis. Infect Immun. 2021 Mar 17;89(4):e00644-20. doi: 10.1128/IAI.00644-20. PMID: 33526564; PMCID: PMC8090971.
    • Dean DA, Gautham G, Siqueira-Neto JL, McKerrow JH, Dorrestein PC, McCall LI. Spatial metabolomics identifies localized chemical changes in heart tissue during chronic cardiac Chagas Disease. PLoS Negl Trop Dis. 2021 Oct 4;15(10):e0009819. doi: 10.1371/journal.pntd.0009819. PMID: 34606502; PMCID: PMC8516257.
    • Parab AR, Thomas D, Lostracco-Johnson S, Siqueira-Neto JL, McKerrow JH, Dorrestein PC, McCall LI. Dysregulation of Glycerophosphocholines in the Cutaneous Lesion Caused by Leishmania major in Experimental Murine Models. Pathogens. 2021 May 13;10(5):593. doi: 10.3390/pathogens10050593. PMID: 34068119; PMCID: PMC8152770.
    • Harris MB, Lesani M, Liu Z, McCall LI. Molecular networking in infectious disease models. Methods Enzymol. 2022;663:341-375. doi: 10.1016/bs.mie.2021.09.018. Epub 2021 Oct 26. PMID: 35168796.
    • Hoffman K, Liu Z, Hossain E, Bottazzi ME, Hotez PJ, Jones KM, McCall LI. Alterations to the Cardiac Metabolome Induced by Chronic cruzi Infection Relate to the Degree of Cardiac Pathology. ACS Infect Dis. 2021 Jun 11;7(6):1638-1649. doi: 10.1021/acsinfecdis.0c00816. Epub 2021 Apr 12. PMID: 33843195; PMCID: PMC8588157.
    • Dean DA, Haffner JJ, Katemauswa M, McCall LI. Chemical Cartography Approaches to Study Trypanosomatid Infection. J Vis Exp. 2022 Jan 21;(179):10.3791/63255. doi: 10.3791/63255. PMID: 35129167; PMCID: PMC8875367.
    • Bernatchez JA, Kil YS, Barbosa da Silva E, Thomas D, McCall LI, Wendt KL, Souza JM, Ackermann J, McKerrow JH, Cichewicz RH, Siqueira-Neto JL. Identification of Leucinostatins from Ophiocordyceps as Antiparasitic Agents against Trypanosoma cruzi. ACS Omega. 2022 Jan 28;7(9):7675-7682. doi: 10.1021/acsomega.1c06347. PMID: 35284725; PMCID: PMC8908367.
    • Katemauswa M, Hossain E, Liu Z, Lesani M, Parab AR, Dean DA, McCall LI. Enabling Quantitative Analysis of Surface Small Molecules for Exposomics and Behavioral Studies. J Am Soc Mass Spectrom. 2022 Mar 2;33(3):412-419. doi: 10.1021/jasms.1c00263. Epub 2022 Jan 27. PMID: 35084848.

    Craig A. Miller

    • Reichard MV, Sanders TL, Weerarathne P, Meinkoth JH, Miller CA, Scimeca RC, Almazán C. Cytauxzoonosis in North America. Pathogens. 2021 Sep 10;10(9):1170. doi: 10.3390/pathogens10091170. PMID: 34578202; PMCID: PMC8469551.
    • Camacho AG, Vajda P, Miller CA, Fernández J. A free-geometry geodynamic modelling of surface gravity changes using Growth-dg software. Sci Rep. 2021 Dec 6;11(1):23442. doi: 10.1038/s41598-021-02769-z. PMID: 34873213; PMCID: PMC8648941.
    • Rudd JM, Selvan MT, Cowan S, Kao YF, Midkiff CC, Ritchey JW, Miller CA. Clinicopathologic features of a feline SARS-CoV-2 infection model parallel acute COVID-19 in humans. bioRxiv [Preprint]. 2021 Apr 23:2021.04.14.439863. doi: 10.1101/2021.04.14.439863. Update in: Viruses. 2021 Aug 05;13(8): PMID: 33880467; PMCID: PMC8057232.
    • Ermann J, Matmusaev M, Haley EK, Braun C, Jost F, Mayer-Wrangowski S, Hsiao P, Ting N, Li L, Terenzio D, Chime J, Lukas S, Patnaude L, Panzenbeck M, Csordas D, Zheng J, Mierz D, Simpson T, King FJ, Klimowicz AP, Mbow ML, Fine JS, Miller CA, Fogal SE, Byrne FR. The potent and selective RIPK2 inhibitor BI 706039 improves intestinal inflammation in the TRUC mouse model of inflammatory bowel disease. Am J Physiol Gastrointest Liver Physiol. 2021 Nov 1;321(5):G500-G512. doi: 10.1152/ajpgi.00163.2021. Epub 2021 Sep 8. PMID: 34494462.
    • Kao YF, Peake B, Madden R, Cowan SR, Scimeca RC, Thomas JE, Reichard MV, Ramachandran A, Miller CA. A probe-based droplet digital polymerase chain reaction assay for early detection of feline acute cytauxzoonosis. Vet Parasitol. 2021 Apr;292:109413. doi: 10.1016/j.vetpar.2021.109413. Epub 2021 Mar 15. Erratum in: Vet Parasitol. 2021 May;293:109428. PMID: 33765571.
    • Rudd JM, Tamil Selvan M, Cowan S, Kao YF, Midkiff CC, Narayanan S, Ramachandran A, Ritchey JW, Miller CA. Clinical and Histopathologic Features of a Feline SARS-CoV-2 Infection Model Are Analogous to Acute COVID-19 in Humans. Viruses. 2021 Aug 5;13(8):1550. doi: 10.3390/v13081550. PMID: 34452415; PMCID: PMC8402899.
    • Kao YF, Peake B, Madden R, Cowan SR, Scimeca RC, Thomas JE, Reichard MV, Ramachandran A, Miller CA. Corrigendum to "A probe-based droplet digital polymerase chain reaction assay for early detection of feline acute cytauxzoonosis" [Vet. Parasitol. 292 (2021) 109413]. Vet Parasitol. 2021 May;293:109428. doi: 10.1016/j.vetpar.2021.109428. Epub 2021 Apr 17. Erratum for: Vet Parasitol. 2021 Apr;292:109413. PMID: 33875275.

    Kenneth E. Miller

    • Anderson MB, Curtis JT, Miller KE. Open-source method of image cytometry in dorsal root ganglia tissue with immunofluorescence. Anal Biochem. 2021 Aug 15;627:114184. doi: 10.1016/j.ab.2021.114184. Epub 2021 Apr 1. PMID: 33811851.
    • Gujar V, Anderson MB, Miller KE, Pande RD, Nawani P, Das S. Separation of Rat Epidermis and Dermis with Thermolysin to Detect Site-Specific Inflammatory mRNA and Protein. J Vis Exp. 2021 Sep 29;(175). doi: 10.3791/59708. PMID: 34661580.
    • Anderson MB, Das S, Miller KE. Subcellular localization of neuronal nuclei (NeuN) antigen in size and calcitonin gene-related peptide (CGRP) populations of dorsal root ganglion (DRG) neurons during acute peripheral inflammation. Neurosci Lett. 2021 Aug 24;760:135974. doi: 10.1016/j.neulet.2021.135974. Epub 2021 Jun 17. PMID: 34146639; PMCID: PMC8355083.

    Sunil More

    • More S, Narayanan S, Patil G, Ghosh P, Pushparaj S, Cooper E, Ritchey J, Cheruvu VK, Kaul A, Ramachandran A. Pooling of Nasopharyngeal Swab Samples To Overcome a Global Shortage of Real-Time Reverse Transcription-PCR COVID-19 Test Kits. J Clin Microbiol. 2021 Mar 19;59(4):e01295-20. doi: 10.1128/JCM.01295-20. PMID: 33500363; PMCID: PMC8092752.
    • Pushparaj S, Zhu Z, Huang C, More S, Liang Y, Lin K, Vaddadi K, Liu L. Regulation of influenza A virus infection by Lnc-PINK1-2:5. J Cell Mol Med. 2022 Feb 24. doi: 10.1111/jcmm.17249. Epub ahead of print. PMID: 35201667.
    • Ramanathan R, Mancini RA, Konda MR, Bailey K, More S, Mafi GG. Evaluating the failure to bloom in dark-cutting and lactate-enhanced beef longissimus steaks. Meat Sci. 2022 Feb;184:108684. doi: 10.1016/j.meatsci.2021.108684. Epub 2021 Sep 24. PMID: 34656000.

    Antonius Oomens

    • Green G, Johnson SM, Costello H, Brakel K, Harder O, Oomens AG, Peeples ME, Moulton HM, Niewiesk S. CX3CR1 Is a Receptor for Human Respiratory Syncytial Virus in Cotton Rats. J Virol. 2021 Jul 26;95(16):e0001021. doi: 10.1128/JVI.00010-21. Epub 2021 Jul 26. PMID: 34037420; PMCID: PMC8312862.
    • Ivanov V, Oomens AGP, Papin JF, Staats R, Reuter DN, Yu Z, Piedra PA, Wellliver RC Sr. Intranasal and intrapulmonary vaccination with an M protein-deficient respiratory syncytial virus (RSV) vaccine improves clinical signs and reduces viral replication in infant baboons after an RSV challenge infection. Vaccine. 2021 Jul 5;39(30):4063-4071. doi: 10.1016/j.vaccine.2021.06.013. Epub 2021 Jun 14. PMID: 34140172.

    Marianna A. Patrauchan

    • King M, Kubo A, Kafer L, Braga R, McLeod D, Khanam S, Conway T, Patrauchan MA. Calcium-Regulated Protein CarP Responds to Multiple Host Signals and Mediates Regulation of Pseudomonas aeruginosa Virulence by Calcium. Appl Environ Microbiol. 2021 Apr 27;87(10):e00061-21. doi: 10.1128/AEM.00061-21. PMID: 33674436; PMCID: PMC8117776.

    Rakhi Rajan

    • Parameshwaran HP, Babu K, Tran C, Guan K, Allen A, Kathiresan V, Qin PZ, Rajan R. The bridge helix of Cas12a imparts selectivity in cis-DNA cleavage and regulates trans-DNA cleavage. FEBS Lett. 2021 Apr;595(7):892-912. doi: 10.1002/1873-3468.14051. Epub 2021 Feb 28. PMID: 33523494; PMCID: PMC8044059.
    • Babu K, Kathiresan V, Kumari P, Newsom S, Parameshwaran HP, Chen X, Liu J, Qin PZ, Rajan R. Coordinated Actions of Cas9 HNH and RuvC Nuclease Domains Are Regulated by the Bridge Helix and the Target DNA Sequence. Biochemistry. 2021 Dec 14;60(49):3783-3800. doi: 10.1021/acs.biochem.1c00354. Epub 2021 Nov 10. PMID: 34757726; PMCID: PMC8675354.

    Ashish Ranjan

    • Munteanu MC, Sethuraman SN, Singh MP, Malayer J, Ranjan A. LncRNA FENDRR Expression Correlates with Tumor Immunogenicity. Genes (Basel). 2021 Jun 10;12(6):897. doi: 10.3390/genes12060897. PMID: 34200642; PMCID: PMC8226633.
    • Li Y, VanOsdol J, Ranjan A, Liu C. A multilayer network-enabled ultrasonic image series analysis approach for online cancer drug delivery monitoring. Comput Methods Programs Biomed. 2022 Jan;213:106505. doi: 10.1016/j.cmpb.2021.106505. Epub 2021 Nov 2. PMID: 34800806.

    Valentin V. Rybenkov

    • D'Cunha N, Moniruzzaman M, Haynes K, Malloci G, Cooper CJ, Margiotta E, Vargiu AV, Uddin MR, Leus IV, Cao F, Parks JM, Rybenkov VV, Ruggerone P, Zgurskaya HI, Walker JK. Mechanistic Duality of Bacterial Efflux Substrates and Inhibitors: Example of Simple Substituted Cinnamoyl and Naphthyl Amides. ACS Infect Dis. 2021 Sep 10;7(9):2650-2665. doi: 10.1021/acsinfecdis.1c00100. Epub 2021 Aug 11. PMID: 34379382; PMCID: PMC8668026.
    • Sarkar R, Petrushenko ZM, Dawson DS, Rybenkov VV. Ycs4 Subunit of Saccharomyces cerevisiae Condensin Binds DNA and Modulates the Enzyme Turnover. Biochemistry. 2021 Nov 16;60(45):3385-3397. doi: 10.1021/acs.biochem.1c00473. Epub 2021 Nov 1. PMID: 34723504; PMCID: PMC8668321.
    • Rybenkov VV, Zgurskaya HI, Ganguly C, Leus IV, Zhang Z, Moniruzzaman M. The Whole Is Bigger than the Sum of Its Parts: Drug Transport in the Context of Two Membranes with Active Efflux. Chem Rev. 2021 May 12;121(9):5597-5631. doi: 10.1021/acs.chemrev.0c01137. Epub 2021 Feb 17. PMID: 33596653; PMCID: PMC8369882.
    • Zhao H, Clevenger AL, Coburn PS, Callegan MC, Rybenkov VV. Condensins are essential for Pseudomonas aeruginosa corneal virulence through their control of lifestyle and virulence programs. Mol Microbiol. 2022 Jan 24. doi: 10.1111/mmi.14883. Epub ahead of print. PMID: 35072315.

    Susan Schroeder

    • Schlick T, Sundberg EJ, Schroeder SJ, Babu MM. Biophysicists' outstanding response to Covid-19. Biophys J. 2021 Mar 16;120(6):E1-E2. doi: 10.1016/j.bpj.2021.02.020. Epub 2021 Mar 4. PMID: 33689685; PMCID: PMC7931721.
    • Schlick T, Sundberg EJ, Schroeder SJ, Babu MM. Biophysicists' continued outstanding response to COVID-19. Biophys J. 2021 Jul 20;120(14):E1. doi: 10.1016/j.bpj.2021.06.019. Epub 2021 Jul 14. PMID: 34265250; PMCID: PMC8279538.

    Karen Wozniak

    • Nelson BN, Beakley SG, Posey S, Conn B, Maritz E, Seshu J, Wozniak KL. Antifungal activity of dendritic cell lysosomal proteins against Cryptococcus neoformans. Sci Rep. 2021 Jun 30;11(1):13619. doi: 10.1038/s41598-021-92991-6. PMID: 34193926; PMCID: PMC8245489.
    • Hawkins AN, Determann BF 2nd, Nelson BN, Wozniak KL. Transcriptional Changes in Pulmonary Phagocyte Subsets Dictate the Outcome Following Interaction With The Fungal Pathogen Cryptococcus neoformans. Front Immunol. 2021 Sep 28;12:722500. doi: 10.3389/fimmu.2021.722500. PMID: 34650554; PMCID: PMC8505728.

    Noha H. Youssef

    • Murphy CL, Sheremet A, Dunfield PF, Spear JR, Stepanauskas R, Woyke T, Elshahed MS, Youssef NH. Genomic Analysis of the Yet-Uncultured Binatota Reveals Broad Methylotrophic, Alkane-Degradation, and Pigment Production Capacities. mBio. 2021 May 18;12(3):e00985-21. doi: 10.1128/mBio.00985-21. PMID: 34006650; PMCID: PMC8262859.
    • Yadav A, Borrelli JC, Elshahed MS, Youssef NH. Genomic Analysis of Family UBA6911 (Group 18 Acidobacteria) Expands the Metabolic Capacities of the Phylum and Highlights Adaptations to Terrestrial Habitats. Appl Environ Microbiol. 2021 Aug 11;87(17):e0094721. doi: 10.1128/AEM.00947-21. Epub 2021 Aug 11. PMID: 34160232; PMCID: PMC8357285.
    • Elkenawy NM, Youssef NH, Aziz RK, Amin MA, Yassin AS. Draft genome sequence of a prodigiosin-hyperproducing Serratia marcescens strain isolated from Cairo, Egypt. G3 (Bethesda). 2021 Sep 27;11(10):jkab284. doi: 10.1093/g3journal/jkab284. PMID: 34568929; PMCID: PMC8473970.
    • Hanafy RA, Youssef NH, Elshahed MS. Paucimyces polynucleatus nov, sp. nov., a novel polycentric genus of anaerobic gut fungi from the faeces of a wild blackbuck antelope. Int J Syst Evol Microbiol. 2021 Jun;71(6). doi: 10.1099/ijsem.0.004832. PMID: 34161217.
    • Yadav A, Hahn CR, Elshahed MS, Youssef NH. Five Metagenome-Assembled Genomes of the Rare Phylum CSSED10-310 from Zodletone Spring (Oklahoma, USA). Microbiol Resour Announc. 2021 Jul;10(26):e0041421. doi: 10.1128/MRA.00414-21. Epub 2021 Jul 1. PMID: 34197190; PMCID: PMC8248873.
    • Murphy CL, Biggerstaff J, Eichhorn A, Ewing E, Shahan R, Soriano D, Stewart S, VanMol K, Walker R, Walters P, Elshahed MS, Youssef NH. Genomic characterization of three novel Desulfobacterota classes expand the metabolic and phylogenetic diversity of the phylum. Environ Microbiol. 2021 Aug;23(8):4326-4343. doi: 10.1111/1462-2920.15614. Epub 2021 Jun 5. PMID: 34056821.
  • Mentor/Core Directors

    Mark Coggehsall

    • Keshari RS, Popescu NI, Silasi R, Regmi G, Lupu C, Simmons JH, Ricardo A, Coggeshall KM, Lupu F. Complement C5 inhibition protects against hemolytic anemia and acute kidney injury in anthrax peptidoglycan-induced sepsis in baboons. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2104347118. doi: 10.1073/pnas.2104347118. PMID: 34507997; PMCID: PMC8449412.

    Tyrrell Conway

    • Conway T. Aspartate in the intestine: dual service as anaerobic electron acceptor and nitrogen source. Environ Microbiol. 2021 May;23(5):2364-2365. doi: 10.1111/1462-2920.15525. Epub 2021 Apr 24. PMID: 33893749; PMCID: PMC8544756.
    • King M, Kubo A, Kafer L, Braga R, McLeod D, Khanam S, Conway T, Patrauchan MA. Calcium-Regulated Protein CarP Responds to Multiple Host Signals and Mediates Regulation of Pseudomonas aeruginosa Virulence by Calcium. Appl Environ Microbiol. 2021 Apr 27;87(10):e00061-21. doi: 10.1128/AEM.00061-21. PMID: 33674436; PMCID: PMC8117776.

    Myron Hinsdale

    • Hayati H, Feng Y, Hinsdale M. Inter-species Variabilities of Droplet Transport, Size Change, and Deposition in Human and Rat Respiratory Systems: An In Silico J Aerosol Sci. 2021 May;154:105761. doi: 10.1016/j.jaerosci.2021.105761. Epub 2021 Jan 23. PMID: 33776134; PMCID: PMC7990120.

    Clinton Jones

    • Wang L, Song K, Hao W, Wu Y, Patil G, Hua F, Sun Y, Huang C, Ritchey J, Jones C, Liu L, Guan JL, Li S. FIP200 restricts RNA virus infection by facilitating RIG-I activation. Commun Biol. 2021 Jul 29;4(1):921. doi: 10.1038/s42003-021-02450-1. PMID: 34326461; PMCID: PMC8322336.
    • Harrison KS, Jones C. Wnt antagonists suppress herpes simplex virus type 1 productive infection. Antiviral Res. 2021 Jul;191:105082. doi: 10.1016/j.antiviral.2021.105082. Epub 2021 May 5. PMID: 33961904; PMCID: PMC8240022.
    • El-Mayet FS, Harrison KS, Jones C. Regulation of Krüppel-Like Factor 15 Expression by Herpes Simplex Virus Type 1 or Bovine Herpesvirus 1 Productive Infection. Viruses. 2021 Jun 15;13(6):1148. doi: 10.3390/v13061148. PMID: 34203849; PMCID: PMC8232590.
    • Ostler JB, Sawant L, Harrison K, Jones C. Regulation of neurotropic herpesvirus productive infection and latency-reactivation cycle by glucocorticoid receptor and stress-induced transcription factors. Vitam Horm. 2021;117:101-132. doi: 10.1016/bs.vh.2021.06.005. Epub 2021 Jul 21. PMID: 34420577; PMCID: PMC8609911.
    • Ostler JB, Jones C. Stress Induced Transcription Factors Transactivate the Herpes Simplex Virus 1 Infected Cell Protein 27 (ICP27) Transcriptional Enhancer. Viruses. 2021 Nov 17;13(11):2296. doi: 10.3390/v13112296. PMID: 34835102; PMCID: PMC8622287.
    • El-Mayet FS, Toomer G, Ostler JB, Harrison KS, Santos VC, Wijesekera N, Stayton E, Ritchey J, Jones C. Progesterone Sporadically Induces Reactivation from Latency in Female Calves but Proficiently Stimulates Bovine Herpesvirus 1 Productive Infection. J Virol. 2022 Mar 9;96(5):e0213021. doi: 10.1128/jvi.02130-21. Epub 2022 Jan 12. PMID: 35019726; PMCID: PMC8906428.
    • Harrison KS, Jones C. Regulation of herpes simplex virus type 1 latency-reactivation cycle and ocular disease by cellular signaling pathways. Exp Eye Res. 2022 Mar 1;218:109017. doi: 10.1016/j.exer.2022.109017. Epub ahead of print. PMID: 35240194.

    Susan Kovats

    • Wu W, Tian L, Zhang W, Booth JL, Ainsua-Enrich E, Kovats S, Brown BR, Metcalf JP. Long-term cigarette smoke exposure dysregulates pulmonary T cell response and IFN-γ protection to influenza virus in mouse. Respir Res. 2021 Apr 20;22(1):112. doi: 10.1186/s12931-021-01713-z. PMID: 33879121; PMCID: PMC8056367.

    Lin Liu

    • Bamunuarachchi G, Pushparaj S, Liu L. Interplay between host non-coding RNAs and influenza viruses. RNA Biol. 2021 May;18(5):767-784. doi: 10.1080/15476286.2021.1872170. Epub 2021 Jan 18. PMID: 33404285; PMCID: PMC8078518.
    • Wang L, Song K, Hao W, Wu Y, Patil G, Hua F, Sun Y, Huang C, Ritchey J, Jones C, Liu L, Guan JL, Li S. FIP200 restricts RNA virus infection by facilitating RIG-I activation. Commun Biol. 2021 Jul 29;4(1):921. doi: 10.1038/s42003-021-02450-1. PMID: 34326461; PMCID: PMC8322336.
    • Pushparaj S, Zhu Z, Huang C, More S, Liang Y, Lin K, Vaddadi K, Liu L. Regulation of influenza A virus infection by Lnc-PINK1-2:5. J Cell Mol Med. 2022 Feb 24. doi: 10.1111/jcmm.17249. Epub ahead of print. PMID: 35201667.
    • Senavirathna LK, Liang Y, Huang C, Yang X, Bamunuarachchi G, Xu D, Dang Q, Sivasami P, Vaddadi K, Munteanu MC, Hewawasam S, Cheresh P, Kamp DW, Liu L. Long Noncoding RNA FENDRR Inhibits Lung Fibroblast Proliferation via a Reduction of β-Catenin. Int J Mol Sci. 2021 Aug 9;22(16):8536. doi: 10.3390/ijms22168536. PMID: 34445242; PMCID: PMC8395204.

    Pamela Lovern

    • Rashdan NA, Zhai B, Lovern PC. Fluid shear stress regulates placental growth factor expression via heme oxygenase 1 and iron. Sci Rep. 2021 Jul 21;11(1):14912. doi: 10.1038/s41598-021-94559-w. PMID: 34290391; PMCID: PMC8295300.

    Jerry W. Ritchey

    • Rudd JM, Selvan MT, Cowan S, Kao YF, Midkiff CC, Ritchey JW, Miller CA. Clinicopathologic features of a feline SARS-CoV-2 infection model parallel acute COVID-19 in humans. bioRxiv [Preprint]. 2021 Apr 23:2021.04.14.439863. doi: 10.1101/2021.04.14.439863. Update in: Viruses. 2021 Aug 05;13(8): PMID: 33880467; PMCID: PMC8057232.
    • Wang L, Song K, Hao W, Wu Y, Patil G, Hua F, Sun Y, Huang C, Ritchey J, Jones C, Liu L, Guan JL, Li S. FIP200 restricts RNA virus infection by facilitating RIG-I activation. Commun Biol. 2021 Jul 29;4(1):921. doi: 10.1038/s42003-021-02450-1. PMID: 34326461; PMCID: PMC8322336.
    • Rudd JM, Tamil Selvan M, Cowan S, Kao YF, Midkiff CC, Narayanan S, Ramachandran A, Ritchey JW, Miller CA. Clinical and Histopathologic Features of a Feline SARS-CoV-2 Infection Model Are Analogous to Acute COVID-19 in Humans. Viruses. 2021 Aug 5;13(8):1550. doi: 10.3390/v13081550. PMID: 34452415; PMCID: PMC8402899.
    • More S, Narayanan S, Patil G, Ghosh P, Pushparaj S, Cooper E, Ritchey J, Cheruvu VK, Kaul A, Ramachandran A. Pooling of Nasopharyngeal Swab Samples To Overcome a Global Shortage of Real-Time Reverse Transcription-PCR COVID-19 Test Kits. J Clin Microbiol. 2021 Mar 19;59(4):e01295-20. doi: 10.1128/JCM.01295-20. PMID: 33500363; PMCID: PMC8092752.
    • El-Mayet FS, Toomer G, Ostler JB, Harrison KS, Santos VC, Wijesekera N, Stayton E, Ritchey J, Jones C. Progesterone Sporadically Induces Reactivation from Latency in Female Calves but Proficiently Stimulates Bovine Herpesvirus 1 Productive Infection. J Virol. 2022 Mar 9;96(5):e0213021. doi: 10.1128/jvi.02130-21. Epub 2022 Jan 12. PMID: 35019726; PMCID: PMC8906428.
    • Wu W, Tian L, Zhang W, Booth JL, Ritchey JW, Wu S, Xu C, Brown BR, Metcalf JP. Early IFN-β administration protects cigarette smoke exposed mice against lethal influenza virus infection without increasing lung inflammation. Sci Rep. 2022 Mar 8;12(1):4080. doi: 10.1038/s41598-022-08066-7. PMID: 35260752; PMCID: PMC8902729.
  • Center Investigators

    Stephen L. Clarke

    • Davis DN, Strong MD, Chambers E, Hart MD, Bettaieb A, Clarke SL, Smith BJ, Stoecker BJ, Lucas EA, Lin D, Chowanadisai W. A role for zinc transporter gene SLC39A12 in the nervous system and beyond. Gene. 2021 Oct 5;799:145824. doi: 10.1016/j.gene.2021.145824. Epub 2021 Jul 9. PMID: 34252531; PMCID: PMC8318780.
    • Fiddler JL, Clarke SL. Evaluation of candidate reference genes for quantitative real-time PCR analysis in a male rat model of dietary iron deficiency. Genes Nutr. 2021 Oct 2;16(1):17. doi: 10.1186/s12263-021-00698-0. PMID: 34600467; PMCID: PMC8487497.

    Ratnakar Deole

    • Truitt C, Hoff WD, Deole R. Health Functionalities of Betaine in Patients With Homocystinuria. Front Nutr. 2021 Sep 9;8:690359. doi: 10.3389/fnut.2021.690359. PMID: 34568401; PMCID: PMC8459993.

    Darren Hagen

    • Fouks B, Brand P, Nguyen HN, Herman J, Camara F, Ence D, Hagen DE, Hoff KJ, Nachweide S, Romoth L, Walden KKO, Guigo R, Stanke M, Narzisi G, Yandell M, Robertson HM, Koeniger N, Chantawannakul P, Schatz MC, Worley KC, Robinson GE, Elsik CG, Rueppell O. The genomic basis of evolutionary differentiation among honey bees. Genome Res. 2021 May 4;31(7):1203–15. doi: 10.1101/gr.272310.120. Epub ahead of print. PMID: 33947700; PMCID: PMC8256857.
    • Ayala-Ortiz CO, Farriester JW, Pratt CJ, Goldkamp AK, Matts J, Hoback WW, Gustafson JE, Hagen DE. Effect of food source availability in the salivary gland transcriptome of the unique burying beetle Nicrophorus pustulatus (Coleoptera: Silphidae). PLoS One. 2021 Sep 23;16(9):e0255660. doi: 10.1371/journal.pone.0255660. PMID: 34555059; PMCID: PMC8460033.

    Chaoqun Huang

    • Wang L, Song K, Hao W, Wu Y, Patil G, Hua F, Sun Y, Huang C, Ritchey J, Jones C, Liu L, Guan JL, Li S. FIP200 restricts RNA virus infection by facilitating RIG-I activation. Commun Biol. 2021 Jul 29;4(1):921. doi: 10.1038/s42003-021-02450-1. PMID: 34326461; PMCID: PMC8322336.
    • Senavirathna LK, Liang Y, Huang C, Yang X, Bamunuarachchi G, Xu D, Dang Q, Sivasami P, Vaddadi K, Munteanu MC, Hewawasam S, Cheresh P, Kamp DW, Liu L. Long Noncoding RNA FENDRR Inhibits Lung Fibroblast Proliferation via a Reduction of β-Catenin. Int J Mol Sci. 2021 Aug 9;22(16):8536. doi: 10.3390/ijms22168536. PMID: 34445242; PMCID: PMC8395204.
    • Pushparaj S, Zhu Z, Huang C, More S, Liang Y, Lin K, Vaddadi K, Liu L. Regulation of influenza A virus infection by Lnc-PINK1-2:5. J Cell Mol Med. 2022 Feb 24. doi: 10.1111/jcmm.17249. Epub ahead of print. PMID: 35201667.

    Haobo Jiang

    • Chen K, Chen J, Tang T, Jiang H, Han Z, Wang L, Alradi MF, Lu S, Wei X, Liu X, Wei Y, Feng C. Characterization and functional analysis of a Relish gene from the Asian corn borer, Ostrinia furnacalis (Guenée). Arch Insect Biochem Physiol. 2021 Oct;108(2):e21841. doi: 10.1002/arch.21841. Epub 2021 Sep 1. PMID: 34468040; PMCID: PMC8453101.
    • Meng Q, Wu PP, Li MM, Shu RH, Zhou GL, Zhang JH, Zhang H, Jiang H, Qin QL, Zou Z. Distinct Responses of Thitarodes xiaojinensis β-1,3-Glucan Recognition Protein-1 and Immulectin-8 to Ophiocordyceps sinensis and Cordyceps militaris J Immunol. 2021 Jul 1;207(1):200-209. doi: 10.4049/jimmunol.2000447. Epub 2021 Jun 23. PMID: 34162722; PMCID: PMC8695634.

    Jerry R. Malayer

    • Ashar HK, Pulavendran S, Rudd JM, Maram P, Achanta M, Chow VTK, Malayer JR, Snider TA, Teluguakula N. Administration of a CXC Chemokine Receptor 2 (CXCR2) Antagonist, SCH527123, Together with Oseltamivir Suppresses NETosis and Protects Mice from Lethal Influenza and Piglets from Swine-Influenza Infection. Am J Pathol. 2021 Apr;191(4):669-685. doi: 10.1016/j.ajpath.2020.12.013. Epub 2021 Jan 14. PMID: 33453177; PMCID: PMC8027923.

    Chongle Pan

    • Wang C, Calle P, Tran Ton NB, Zhang Z, Yan F, Donaldson AM, Bradley NA, Yu Z, Fung KM, Pan C, Tang Q. Deep-learning-aided forward optical coherence tomography endoscope for percutaneous nephrostomy guidance. Biomed Opt Express. 2021 Mar 29;12(4):2404-2418. doi: 10.1364/BOE.421299. PMID: 33996237; PMCID: PMC8086467.
    • Kieft B, Li Z, Bryson S, Hettich RL, Pan C, Mayali X, Mueller RS. Phytoplankton exudates and lysates support distinct microbial consortia with specialized metabolic and ecophysiological traits. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2101178118. doi: 10.1073/pnas.2101178118. PMID: 34620710; PMCID: PMC8521717.
    • Saha P, Lin F, Thibivilliers S, Xiong Y, Pan C, Bartley LE. Phenylpropanoid Biosynthesis Gene Expression Precedes Lignin Accumulation During Shoot Development in Lowland and Upland Switchgrass Genotypes. Front Plant Sci. 2021 Aug 9;12:640930. doi: 10.3389/fpls.2021.640930. PMID: 34434200; PMCID: PMC8380989.
    • Badré A, Zhang L, Muchero W, Reynolds JC, Pan C. Deep neural network improves the estimation of polygenic risk scores for breast cancer. J Hum Genet. 2021 Apr;66(4):359-369. doi: 10.1038/s10038-020-00832-7. Epub 2020 Oct 2. PMID: 33009504.
    • Yates TB, Feng K, Zhang J, Singan V, Jawdy SS, Ranjan P, Abraham PE, Barry K, Lipzen A, Pan C, Schmutz J, Chen JG, Tuskan GA, Muchero W. The Ancient Salicoid Genome Duplication Event: A Platform for Reconstruction of De Novo Gene Evolution in Populus trichocarpa. Genome Biol Evol. 2021 Sep 1;13(9):evab198. doi: 10.1093/gbe/evab198. PMID: 34469536; PMCID: PMC8445398.
    • Wang C, Reynolds JC, Calle P, Ladymon AD, Yan F, Yan Y, Ton S, Fung KM, Patel SG, Yu Z, Pan C, Tang Q. Computer-aided Veress needle guidance using endoscopic optical coherence tomography and convolutional neural networks. J Biophotonics. 2022 Feb 1:e202100347. doi: 10.1002/jbio.202100347. Epub ahead of print. PMID: 35103420.

    Carey Pope

    • Herriage S, Chen G, Pope C. Concentration-dependent effects of chlorpyrifos oxon on peroxisome proliferator-activated receptor signaling in MCF-7 cells. Toxicol In Vitro. 2022 Feb;78:105268. doi: 10.1016/j.tiv.2021.105268. Epub 2021 Oct 29. PMID: 34756920; PMCID: PMC8710288.

    Charles V. Rice

    • Panlilio H, Rice CV. The role of extracellular DNA in the formation, architecture, stability, and treatment of bacterial biofilms. Biotechnol Bioeng. 2021 Jun;118(6):2129-2141. doi: 10.1002/bit.27760. Epub 2021 Mar 27. PMID: 33748946; PMCID: PMC8667714.
    • Panlilio H, Lam AK, Heydarian N, Haight T, Wouters CL, Moen EL, Rice CV. Dual-Function Potentiation by PEG-BPEI Restores Activity of Carbapenems and Penicillins against Carbapenem-Resistant Enterobacteriaceae. ACS Infect Dis. 2021 Jun 11;7(6):1657-1665. doi: 10.1021/acsinfecdis.0c00863. Epub 2021 May 4. PMID: 33945257; PMCID: PMC8689638.
    • Moen EL, Lam AK, Pusavat J, Wouters CL, Panlilio H, Heydarian N, Peng Z, Lan Y, Rice CV. Dimerization of 600 Da branched polyethylenimine improves β-lactam antibiotic potentiation against antibiotic-resistant Staphylococcus epidermidis and Pseudomonas aeruginosa. Chem Biol Drug Des. 2021 Dec 19. doi: 10.1111/cbdd.14009. Epub ahead of print. PMID: 34923750.

    Kenneth M. Smith

    • Huang L, Fang M, Cupp-Sutton KA, Wang Z, Smith K, Wu S. Spray-Capillary-Based Capillary Electrophoresis Mass Spectrometry for Metabolite Analysis in Single Cells. Anal Chem. 2021 Mar 16;93(10):4479-4487. doi: 10.1021/acs.analchem.0c04624. Epub 2021 Mar 1. PMID: 33646748; PMCID: PMC8323477.
    • Yu D, Wang Z, Cupp-Sutton KA, Guo Y, Kou Q, Smith K, Liu X, Wu S. Quantitative Top-Down Proteomics in Complex Samples Using Protein-Level Tandem Mass Tag Labeling. J Am Soc Mass Spectrom. 2021 Jun 2;32(6):1336-1344. doi: 10.1021/jasms.0c00464. Epub 2021 Mar 16. PMID: 33725447; PMCID: PMC8323476.
    • Smith K, Garman L, Norris K, Muther J, Duke A, Engler RJM, Nelson MR, Collins LC, Spooner C, Guthridge C, James JA. Insufficient Anthrax Lethal Toxin Neutralization Is Associated with Antibody Subclass and Domain Specificity in the Plasma of Anthrax-Vaccinated Individuals. Microorganisms. 2021 Jun 2;9(6):1204. doi: 10.3390/microorganisms9061204. PMID: 34199431; PMCID: PMC8229884.
    • Fang M, Wang Z, Norris K, James JA, Wu S, Smith K. Hydrogen-Deuterium Exchange Mass Spectrometry Reveals a Novel Binding Region of a Neutralizing Fully Human Monoclonal Antibody to Anthrax Protective Antigen. Toxins (Basel). 2022 Jan 25;14(2):92. doi: 10.3390/toxins14020092. PMID: 35202120; PMCID: PMC8877668.

    Timothy A. Snider

    • Ashar HK, Pulavendran S, Rudd JM, Maram P, Achanta M, Chow VTK, Malayer JR, Snider TA, Teluguakula N. Administration of a CXC Chemokine Receptor 2 (CXCR2) Antagonist, SCH527123, Together with Oseltamivir Suppresses NETosis and Protects Mice from Lethal Influenza and Piglets from Swine-Influenza Infection. Am J Pathol. 2021 Apr;191(4):669-685. doi: 10.1016/j.ajpath.2020.12.013. Epub 2021 Jan 14. PMID: 33453177; PMCID: PMC8027923.
    • Van Remmen H, Freeman WM, Miller BF, Kinter M, Wren JD, Chiao A, Towner RA, Snider TA, Sonntag WE, Richardson A. Oklahoma Nathan Shock Aging Center - assessing the basic biology of aging from genetics to protein and function. Geroscience. 2021 Oct;43(5):2183-2203. doi: 10.1007/s11357-021-00454-7. Epub 2021 Oct 4. PMID: 34606039; PMCID: PMC8599778.

    Lijun Xia

    • Tang C, Wang L, Sheng Y, Zheng Z, Xie Z, Wu F, You T, Ren L, Xia L, Ruan C, Zhu L. CLEC-2-dependent platelet subendothelial accumulation by flow disturbance contributes to atherogenesis in mice. Theranostics. 2021 Oct 3;11(20):9791-9804. doi: 10.7150/thno.64601. PMID: 34815786; PMCID: PMC8581433.
    • Zhou L, Yu T, Yang F, Han J, Zuo B, Huang L, Bai X, Jiang M, Wu D, Chen S, Xia L, Ruan J, Ruan C. G Protein-Coupled Estrogen Receptor Agonist G-1 Inhibits Mantle Cell Lymphoma Growth in Preclinical Models. Front Oncol. 2021 Jun 15;11:668617. doi: 10.3389/fonc.2021.668617. PMID: 34211844; PMCID: PMC8239310.
    • Hoover C, Kondo Y, Shao B, McDaniel MJ, Lee R, McGee S, Whiteheart S, Bergmeier W, McEver RP, Xia L. Heightened activation of embryonic megakaryocytes causes aneurysms in the developing brain of mice lacking podoplanin. Blood. 2021 May 20;137(20):2756-2769. doi: 10.1182/blood.2020010310. PMID: 33619517; PMCID: PMC8138551.
    • Kondo Y, Larabee JL, Gao L, Shi H, Shao B, Hoover CM, McDaniel JM, Ho YC, Silasi-Mansat R, Archer-Hartmann SA, Azadi P, Srinivasan RS, Rezaie AR, Borczuk A, Laurence JC, Lupu F, Ahamed J, McEver RP, Papin JF, Yu Z, Xia L. L-SIGN is a receptor on liver sinusoidal endothelial cells for SARS-CoV-2 virus. JCI Insight. 2021 Jul 22;6(14):e148999. doi: 10.1172/jci.insight.148999. PMID: 34291736; PMCID: PMC8410055.
    • Jiang Y, Tang Y, Hoover C, Kondo Y, Huang D, Restagno D, Shao B, Gao L, Michael McDaniel J, Zhou M, Silasi-Mansat R, McGee S, Jiang M, Bai X, Lupu F, Ruan C, Marth JD, Wu D, Han Y, Xia L. Kupffer cell receptor CLEC4F is important for the destruction of desialylated platelets in mice. Cell Death Differ. 2021 Nov;28(11):3009-3021. doi: 10.1038/s41418-021-00797-w. Epub 2021 May 15. PMID: 33993195; PMCID: PMC8564511.
    • Shao B, Hoover CM, Shi H, Kondo Y, Lee RH, Chen J, Shan X, Song J, McDaniel M, Zhou M, McGee S, Vanhoorelbeke K, Bergmeier W, López JA, George JN, Xia L. Deletion of platelet CLEC-2 decreases GPIba-mediated integrin aIIbb3 activation and decreases thrombosis in TTP. Blood. 2022 Feb 14:blood.2021012896. doi: 10.1182/blood.2021012896. Epub ahead of print. PMID: 35157766.

    Xiangming Xiao

    • Christian JI, Basara JB, Hunt ED, Otkin JA, Furtado JC, Mishra V, Xiao X, Randall RM. Global distribution, trends, and drivers of flash drought occurrence. Nat Commun. 2021 Nov 3;12(1):6330. doi: 10.1038/s41467-021-26692-z. PMID: 34732727; PMCID: PMC8566603.
    • Cornell CR, Zhang Y, Van Nostrand JD, Wagle P, Xiao X, Zhou J. Temporal Changes of Virus-Like Particle Abundance and Metagenomic Comparison of Viral Communities in Cropland and Prairie Soils. mSphere. 2021 Jun 30;6(3):e0116020. doi: 10.1128/mSphere.01160-20. Epub 2021 Jun 2. PMID: 34077260; PMCID: PMC8265675.
    • Zhao M, Yang J, Zhao N, Xiao X, Yue T, Wilson JP. Estimation of the relative contributions of forest areal expansion and growth to China's forest stand biomass carbon sequestration from 1977 to 2018. J Environ Manage. 2021 Dec 15;300:113757. doi: 10.1016/j.jenvman.2021.113757. Epub 2021 Sep 16. PMID: 34537562.
    • Yang J, Wang Y, Xue B, Li Y, Xiao X, Xia JC, He B. Contribution of urban ventilation to the thermal environment and urban energy demand: Different climate background perspectives. Sci Total Environ. 2021 Nov 15;795:148791. doi: 10.1016/j.scitotenv.2021.148791. Epub 2021 Jun 29. PMID: 34237531.
    • Liu F, Xiao X, Qin Y, Yan H, Huang J, Wu X, Zhang Y, Zou Z, Doughty RB. Large spatial variation and stagnation of cropland gross primary production increases the challenges of sustainable grain production and food security in China. Sci Total Environ. 2022 Mar 10;811:151408. doi: 10.1016/j.scitotenv.2021.151408. Epub 2021 Nov 4. PMID: 34742987.
    • Wang S, Gao J, Guo L, Nie X, Xiao X. Meteorological Influences on Spatiotemporal Variation of PM2.5 Concentrations in Atmospheric Pollution Transmission Channel Cities of the Beijing-Tianjin-Hebei Region, China. Int J Environ Res Public Health. 2022 Jan 30;19(3):1607. doi: 10.3390/ijerph19031607. PMID: 35162629; PMCID: PMC8834796.

    Guolong Zhang

    • Wu Z, Huang S, Li T, Li N, Han D, Zhang B, Xu ZZ, Zhang S, Pang J, Wang S, Zhang G, Zhao J, Wang J. Gut microbiota from green tea polyphenol-dosed mice improves intestinal epithelial homeostasis and ameliorates experimental colitis. Microbiome. 2021 Sep 7;9(1):184. doi: 10.1186/s40168-021-01115-9. PMID: 34493333; PMCID: PMC8424887.
    • Yang Q, Liu J, Robinson KJ, Whitmore MA, Stewart SN, Zhang G. Perturbations of the ileal mycobiota by necrotic enteritis in broiler chickens. J Anim Sci Biotechnol. 2021 Oct 9;12(1):107. doi: 10.1186/s40104-021-00628-5. PMID: 34625122; PMCID: PMC8501549.
    • Robinson K, Yang Q, Li H, Zhang L, Aylward B, Arsenault RJ, Zhang G. Butyrate and Forskolin Augment Host Defense, Barrier Function, and Disease Resistance Without Eliciting Inflammation. Front Nutr. 2021 Oct 27;8:778424. doi: 10.3389/fnut.2021.778424. PMID: 34778349; PMCID: PMC8579826.
    • Yang Q, Liu J, Wang X, Robinson K, Whitmore MA, Stewart SN, Zhao J, Zhang G. Identification of an Intestinal Microbiota Signature Associated With the Severity of Necrotic Enteritis. Front Microbiol. 2021 Aug 19;12:703693. doi: 10.3389/fmicb.2021.703693. PMID: 34489892; PMCID: PMC8418326.
    • Yang Q, Fong LA, Lyu W, Sunkara LT, Xiao K, Zhang G. Synergistic Induction of Chicken Antimicrobial Host Defense Peptide Gene Expression by Butyrate and Sugars. Front Microbiol. 2021 Dec 9;12:781649. doi: 10.3389/fmicb.2021.781649. PMID: 34956146; PMCID: PMC8696121.
    • Yang Q, Whitmore MA, Robinson K, Lyu W, Zhang G. Butyrate, Forskolin, and Lactose Synergistically Enhance Disease Resistance by Inducing the Expression of the Genes Involved in Innate Host Defense and Barrier Function. Antibiotics (Basel). 2021 Sep 27;10(10):1175. doi: 10.3390/antibiotics10101175. PMID: 34680756; PMCID: PMC8532606.
    • Yang Q, Burkardt AC, Sunkara LT, Xiao K, Zhang G. Natural Cyclooxygenase-2 Inhibitors Synergize With Butyrate to Augment Chicken Host Defense Peptide Gene Expression. Front Immunol. 2022 Feb 22;13:819222. doi: 10.3389/fimmu.2022.819222. PMID: 35273602; PMCID: PMC8902166.
    • Yang Q, Chen B, Robinson K, Belem T, Lyu W, Deng Z, Ramanathan R, Zhang G. Butyrate in combination with forskolin alleviates necrotic enteritis, increases feed efficiency, and improves carcass composition of broilers. J Anim Sci Biotechnol. 2022 Feb 10;13(1):3. doi: 10.1186/s40104-021-00663-2. PMID: 35139922; PMCID: PMC8830124.
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