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Respiratory and Infectious Diseases

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  • Pilot/Project Leaders
    1. Chowdhury AA, Rodgers K, Godbole NM, Awasthi S. Stability and structure-activity relationship of the SPA4 peptide under ambient and stressed conditions of lung injury. RSC Adv. 2023 Jun 21;13(27):18864-18877. doi: 10.1039/d3ra02918b. PMID: 37350860; PMCID: PMC10282593.
    2. Awasthi S, Singh B, Ramani V, Godbole NM, King C. Involvement of endoplasmic reticulum and histone proteins in immunomodulation by TLR4-interacting SPA4 peptide against Escherichia coli. Infect Immun. 2023 Dec 12;91(12):e0031123. doi: 10.1128/iai.00311-23. Epub 2023 Nov 1. PMID: 37909750; PMCID: PMC10714950.
    3. Severance ZC, Nuñez JI, Le-McClain AT, Malinky CA, Bensen RC, Fogle RS, Manginelli GW, Sakers SH, Falcon EC, Bui RH, Snead KJ, Bourne CR, Burgett AWG. Structure-Activity Relationships of Ligand Binding to Oxysterol-Binding Protein (OSBP) and OSBP-Related Protein 4. J Med Chem. 2023 Mar 23;66(6):3866-3875. doi: 10.1021/acs.jmedchem.2c01025. Epub 2023 Mar 14. PMID: 36916802; PMCID: PMC10786236.
    4. Ruan S, Tu CH, Bourne CR. Friend or Foe: Protein Inhibitors of DNA Gyrase. Biology (Basel). 2024 Jan 29;13(2):84. doi: 10.3390/biology13020084. PMID: 38392303; PMCID: PMC10886550.
    5. Subramaniyan B, Larabee JL, Bodas M, Moore AR, Burgett AWG, Papin JF, Walters MS. Inhibition of the Cellular Deubiquitinase UCHL1 Suppresses SARS-CoV-2 Replication. Am J Respir Cell Mol Biol. 2023 Sep;69(3):367-370. doi: 10.1165/rcmb.2023-0076LE. PMID: 37655875; PMCID: PMC10503309.
    6. Gardner ED, Johnson BP, Dimas DA, McClurg HE, Severance ZC, Burgett AW, Singh S. Unlocking New Prenylation Modes: Azaindoles as a New Substrate Class for Indole Prenyltransferases. ChemCatChem. 2023 Oct 6;15(19):e202300650. doi: 10.1002/cctc.202300650. Epub 2023 Aug 10. PMID: 37954549; PMCID: PMC10634513.
    7. Bush SR, Sanders S, Frey N, Hamm CW, Toews M, Winburn S, Fayard EJ, Rodriguez A, Boyne NS, Osborne JS, Cabeen MT. Temporal σBstress-response profiles impact Bacillus subtilis mSphere. 2024 Feb 28;9(2):e0071923. doi: 10.1128/msphere.00719-23. Epub 2024 Jan 18. PMID: 38236030.
    8. Pan S, Erdmann M, Terrell J, Cabeen MT. A putative lipase affects Pseudomonas aeruginosabiofilm matrix production. mSphere. 2023 Oct 24;8(5):e0037423. doi: 10.1128/msphere.00374-23. Epub 2023 Sep 27. PMID: 37754547; PMCID: PMC10597414.
    9. Underhill SAM, Pan S, Erdmann M, Cabeen MT. PtsN in Pseudomonas aeruginosa Is Phosphorylated by Redundant Upstream Proteins and Impacts Virulence-Related Genes. J Bacteriol. 2023 May 25;205(5):e0045322. doi: 10.1128/jb.00453-22. Epub 2023 Apr 19. PMID: 37074168; PMCID: PMC10210985.
    10. Abisado-Duquea RG, McKee BM, Townsend KA, Woods K, Koirala P, Holder AJ, Craddock VD, Cabeen MT, Chandler JR. Tobramycin adaptation alters the antibiotic susceptibility of Pseudomonas aeruginosa quorum sensing-null mutants. bioRxiv [Preprint]. 2023 Mar 19:2023.01.13.523864. doi: 10.1101/2023.01.13.523864. Update in: J Bacteriol. 2023 May 16;:e0011423. PMID: 36711731; PMCID: PMC9882136.
    11. Abisado-Duque RG, Townsend KA, Mckee BM, Woods K, Koirala P, Holder AJ, Craddock VD, Cabeen M, Chandler JR. An Amino Acid Substitution in Elongation Factor EF-G1A Alters the Antibiotic Susceptibility of Pseudomonas aeruginosa LasR-Null Mutants. J Bacteriol. 2023 Jun 27;205(6):e0011423. doi: 10.1128/jb.00114-23. Epub 2023 May 16. PMID: 37191503; PMCID: PMC10294626.
    12. Yahya AH, Harston SR, Colton WL, Cabeen MT. Distinct Screening Approaches Uncover PA14_36820 and RecA as Negative Regulators of Biofilm Phenotypes in Pseudomonas aeruginosa PA14. Microbiol Spectr. 2023 Mar 27;11(2):e0377422. doi: 10.1128/spectrum.03774-22. Epub ahead of print. PMID: 36971546; PMCID: PMC10100956.
    13. Guthrie, C.M., X. Tan, A.C. Meeker, A.E. Self, L. Liu, and Cheng. 2023. Engineering a dual vaccine against COVID-19 and tuberculosis. Front Cell Infect Microbiol 13:1273019. (P20GM103648)
    14. Kotey, S.K., X. Tan, O. Fleming, R.R. Kasiraju, A.L. Dagnell, K.N. Van Pelt, J. Rogers, S.D. Hartson, N. Thadathil, R. Selvarani, R. Ranjit, S. Logan, S.S. Deepa, A. Richardson, and Cheng. 2024. Intracellular iron accumulation facilitates mycobacterial infection in old mouse macrophages. Geroscience. Apr;46(2):2739-2754. (P20GM103648)
    15. Charlie A. Vermeire, Xuejuan Tan, Yurong Liang, Stephen K. Kotey, Janet Rogers, Steven D. Hartson, Lin Liu, and Yong Cheng. 2024. Mycobacterium abscessus Extracellular Vesicles Increase Mycobacterial Resistance to Clarithromycin in vitro. Proteomics. Jan 18:e2300332. (P20GM103648)
    16. Barrett MR, Scott Davis M. Conditioning-induced expression of novel glucose transporters in canine skeletal muscle homogenate. PLoS One. 2023 May 3;18(5):e0285424. doi: 10.1371/journal.pone.0285424. PMID: 37134107; PMCID: PMC10155965.
    17. Zhang F, Ji Q, Chaturvedi J, Morales M, Mao Y, Meng X, Dong L, Deng J, Qian SB, Xiang Y. Human SAMD9 is a poxvirus-activatable anticodon nuclease inhibiting codon-specific protein synthesis. Sci Adv. 2023 Jun 9;9(23):eadh8502. doi: 10.1126/sciadv.adh8502. Epub 2023 Jun 7. PMID: 37285440; PMCID: PMC10246899.
    18. Merfeld T, Peng S, Keegan BM, Crowley VM, Brackett CM, Gutierrez A, McCann NR, Reynolds TS, Rhodes MC, Byrd KM, Deng J, Matts RL, Blagg BSJ. Elucidation of novel TRAP1-Selective inhibitors that regulate mitochondrial processes. Eur J Med Chem. 2023 Oct 5;258:115531. doi: 10.1016/j.ejmech.2023.115531. Epub 2023 Jun 5. PMID: 37307624; PMCID: PMC10529355.
    19. Kolewe EL, Padhye S, Woodward IR, Feng Y, Briddell JW, Fromen CA. A Pediatric Upper Airway Library to Evaluate Interpatient Variability of In Silico Aerosol Deposition. AAPS PharmSciTech. 2023 Jul 31;24(6):162. doi: 10.1208/s12249-023-02619-3. PMID: 37523076; PMCID: PMC10660588.
    20. Bartlett BA, Feng Y, Fromen CA, Ford Versypt AN. Computational fluid dynamics modeling of aerosol particle transport through lung airway mucosa. Comput Chem Eng. 2023 Nov;179:108458. doi: 10.1016/j.compchemeng.2023.108458. Epub 2023 Oct 16. PMID: 37946856; PMCID: PMC10634618.
    21. Bourlon M, Feng Y, Garcia-Contreras L. Designing Aerosol Therapies Based on the Integrated Evaluation of In Vitro, In Vivo, and In Silico Data. Pharmaceutics. 2023 Jun 9;15(6):1695. doi: 10.3390/pharmaceutics15061695. PMID: 37376143; PMCID: PMC10305213.
    22. Roe MM, Do T, Turner S, Jevitt AM, Chlebicz M, White K, Oomens AGP, Rankin S, Kovats S, Gappa-Fahlenkamp H. Blood myeloid cells differentiate to lung resident cells and respond to pathogen stimuli in a 3D human tissue-engineered lung model. Front Bioeng Biotechnol. 2023 Jul 7;11:1212230. doi: 10.3389/fbioe.2023.1212230. PMID: 37485324; PMCID: PMC10361305.
    23. Bourlon, M., Garcia-Contreras, L. (2023). In vitro activity of OHet72 alone or in combination with first- and second-line drugs against Mycobacterium tuberculosis: Insight into its mechanism of action. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 36(6), A13.
    24. Beathard, A., Garcia-Contreras, L. (2023). Selection of a nebulizer for the efficient treatment of tuberculosis infected mice with aerosolized OHet72 nanocrystals. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 36(6), A16
    25. Rochowski MT, Jayathilake K, Balcerak JM, Selvan MT, Gunasekara S, Miller C, Rudd JM, Lacombe VA. Impact of Delta SARS-CoV-2 Infection on Glucose Metabolism: Insights on Host Metabolism and Virus Crosstalk in a Feline Model. Viruses. 2024 Feb 15;16(2):295. doi: 10.3390/v16020295. PMID: 38400070; PMCID: PMC10893195.
    26. Sankey N, Merrick H, Singh P, Rogers J, Reddi A, Hartson SD, Mitra A. Role of the Mycobacterium tuberculosis ESX-4 Secretion System in Heme Iron Utilization and Pore Formation by PPE Proteins. mSphere. 2023 Apr 20;8(2):e0057322. doi: 10.1128/msphere.00573-22. Epub 2023 Feb 7. PMID: 36749044; PMCID: PMC10117145.
    27. Kolodkin-Gal I, Parsek MR, Patrauchan MA. The roles of calcium signaling and calcium deposition in microbial multicellularity. Trends Microbiol. 2023 Dec;31(12):1225-1237. doi: 10.1016/j.tim.2023.06.005. Epub 2023 Jul 8. PMID: 37429751; PMCID: PMC10772221.
    28. Tiwari, A. Sharma, R. Braga**, E. Garcia, R. Appiah, R. Fleeman, B.H. Abiaita, M.A. Patrauchan, and W.T. Doerrler “Klebsiella pneumoniae YgjA and YghB have redundant roles in divalent cation homeostasis and macrophage resistance” Microbiology Spectrum, 2023
    29. Burch-Konda J, Kayastha BB, Kubo A, Achour M, Hull M, Braga R, Winton L, Rogers RR, McCoy J, Lutter EI, Patrauchan MA. EF-Hand Calcium Sensor, EfhP, Controls Transcriptional Regulation of Iron Uptake by Calcium in Pseudomonas aeruginosa. bioRxiv [Preprint]. 2024 Jan 10:2024.01.09.574892. doi: 10.1101/2024.01.09.574892. PMID: 38260268; PMCID: PMC10802428.
    30. Daniel R. Reed, Katherine Nehmzow, Martha A. Essandoh, Mohammad A. Ebqa’ai, Toby L. Nelson, Erika I. Lutter, Gabriel A. Cook, Franklin R. Champlin. Relationship between cell envelope ultrastructure and the antibacterial properties of 3 a novel hydrophobic eumelanin-inspired 4 derivative. Frontiers in Microbiology. 2023.
    31. Park JH, Prasad V, Newsom S, Najar F, Rajan R. idMotif: An Interactive Motif Identification in Protein Sequences. IEEE Comput Graph Appl. 2023 Dec 21;PP. doi: 10.1109/MCG.2023.3345742. Epub ahead of print. PMID: 38127603.
    32. Newsom SN, Wang DS, Rostami S, Schuster I, Parameshwaran HP, Joseph YG, Qin PZ, Liu J, Rajan R. Differential Divalent Metal Binding by SpyCas9's RuvC Active Site Contributes to Nonspecific DNA Cleavage. CRISPR J. 2023 Dec;6(6):527-542. doi: 10.1089/crispr.2023.0022. PMID: 38108519; PMCID: PMC10753984.
    33. Gunderman A, Montayre R, Ranjan A, Chen Y. Review of Robot-Assisted HIFU Therapy. Sensors (Basel). 2023 Apr 3;23(7):3707. doi: 10.3390/s23073707. PMID: 37050766; PMCID: PMC10098661.
    34. Ashar H, Ranjan A. Immunomodulation and targeted drug delivery with high intensity focused ultrasound (HIFU): Principles and mechanisms. Pharmacol Ther. 2023 Apr;244:108393. doi: 10.1016/j.pharmthera.2023.108393. Epub 2023 Mar 23. PMID: 36965581.
    35. Singh A, Ashar H, Butcher JT, Ranjan A. Age-associated changes in the gut microbiome impact efficacy of tumor immunomodulatory treatments. Exp Gerontol. 2023 Oct 1;181:112268. doi: 10.1016/j.exger.2023.112268. Epub 2023 Aug 29. PMID: 37572993.
    36. Ashar H, Singh A, Kishore D, Neel T, More S, Liu C, Dugat D, Ranjan A. Enabling Chemo-Immunotherapy with HIFU in Canine Cancer Patients. Ann Biomed Eng. 2023 May 10. doi: 10.1007/s10439-023-03194-1. Epub ahead of print. PMID: 37162696.
    37. Singh A, Ranjan A. Adrenergic receptor signaling regulates the CD40-receptor mediated anti-tumor immunity. Front Immunol. 2023 Mar 15;14:1141712. doi: 10.3389/fimmu.2023.1141712. PMID: 37006295; PMCID: PMC10050348.
    38. Chandrasekar SV, Singh A, Ranjan A. Overcoming Resistance to Immune Checkpoint Inhibitor Therapy Using Calreticulin-Inducing Nanoparticle. Pharmaceutics. 2023 Jun 9;15(6):1693. doi: 10.3390/pharmaceutics15061693. PMID: 37376141; PMCID: PMC10302072.
    39. Gervasoni S, Mehla J, Bergen CR, Leus IV, Margiotta E, Malloci G, Bosin A, Vargiu AV, Lomovskaya O, Rybenkov VV, Ruggerone P, Zgurskaya HI. Molecular determinants of avoidance and inhibition of Pseudomonas aeruginosaMexB efflux pump. mBio. 2023 Aug 31;14(4):e0140323. doi: 10.1128/mbio.01403-23. Epub 2023 Jul 26. PMID: 37493633; PMCID: PMC10470492.
    40. Hu Z, Leus IV, Chandar B, Sherborne BS, Avila QP, Rybenkov VV, Zgurskaya HI, Duerfeldt AS. Correction to "Structure-Uptake Relationship Studies of Oxazolidinones in Gram-Negative ESKAPE Pathogens". J Med Chem. 2023 Oct 12;66(19):13858. doi: 10.1021/acs.jmedchem.3c01679. Epub 2023 Sep 21. Erratum for: J Med Chem. 2022 Oct 27;65(20):14144-14179. PMID: 37733930.
    41. Leus IV, Weeks JW, Bonifay V, Shen Y, Yang L, Cooper CJ, Nath D, Duerfeldt AS, Smith JC, Parks JM, Rybenkov VV, Zgurskaya HI. Author Correction: Property space mapping of Pseudomonas aeruginosa permeability to small molecules. Sci Rep. 2023 Jun 1;13(1):8918. doi: 10.1038/s41598-023-35960-5. Erratum for: Sci Rep. 2022 May 17;12(1):8220. PMID: 37264107; PMCID: PMC10235027.
    42. Schroeder SJ. Insights into nucleic acid helix formation from infrared spectroscopy. Biophys J. 2024 Jan 16;123(2):115-117. doi: 10.1016/j.bpj.2023.12.017. Epub 2023 Dec 21. PMID: 38130057; PMCID: PMC10808036.
    43. Conn BN, Wozniak KL. Innate Pulmonary Phagocytes and Their Interactions with Pathogenic Cryptococcus J Fungi (Basel). 2023 May 27;9(6):617. doi: 10.3390/jof9060617. PMID: 37367553; PMCID: PMC10299524.
    44. Goughenour KD, Nair AS, Xu J, Olszewski MA, Wozniak KL. Dendritic Cells: Multifunctional Roles in Host Defenses to Cryptococcus J Fungi (Basel). 2023 Oct 26;9(11):1050. doi: 10.3390/jof9111050. PMID: 37998856; PMCID: PMC10672120.
    45. Conn BN, Lieberman JA, Chatman P, Cotton K, Essandoh MA, Ebqa'ai M, Nelson TL, Wozniak K Antifungal activity of eumelanin-inspired indoylenepheyleneethynylene against Cryptococcus neoformans. Front Microbiol. 2024 Jan 16;14:1339303. doi: 10.3389/fmicb.2023.1339303. PMID: 38293553; PMCID: PMC10826398.
    46. Alake SE, Lightfoot S, Wozniak K, Lin D, Chowanadisai W, Smith BJ, Lucas EA. Wheat Germ Supplementation Reduces Inflammation and Gut Epithelial Barrier Dysfunction in Female Interleukin-10 Knockout Mice Fed a Pro-Atherogenic Diet. J Nutr. 2023 Mar;153(3):870-879. doi: 10.1016/j.tjnut.2023.01.008. Epub 2023 Jan 9. PMID: 36813578.
    47. Alake SE, Ice J, Robinson K, Price P, Hatter B, Wozniak K, Lin D, Chowanadisai W, Smith BJ, Lucas EA. Reduced estrogen signaling contributes to bone loss and cardiac dysfunction in interleukin-10 knockout mice. Physiol Rep. 2024 Jan;12(1):e15914. doi: 10.14814/phy2.15914. PMID: 38217044; PMCID: PMC10787104.
    48. Meili CH, Jones AL, Arreola AX, Habel J, Pratt CJ, Hanafy RA, Wang Y, Yassin AS, TagElDein MA, Moon CD, Janssen PH, Shrestha M, Rajbhandari P, Nagler M, Vinzelj JM, Podmirseg SM, Stajich JE, Goetsch AL, Hayes J, Young D, Fliegerova K, Grilli DJ, Vodička R, Moniello G, Mattiello S, Kashef MT, Nagy YI, Edwards JA, Dagar SS, Foote AP, Youssef NH, Elshahed MS. Patterns and determinants of the global herbivorous mycobiome. Nat Commun. 2023 Jun 26;14(1):3798. doi: 10.1038/s41467-023-39508-z. PMID: 37365172; PMCID: PMC10293281.
    49. Jones AL, Pratt CJ, Meili CH, Soo RM, Hugenholtz P, Elshahed MS, Youssef NH. Anaerobic gut fungal communities in marsupial hosts. mBio. 2024 Feb 14;15(2):e0337023. doi: 10.1128/mbio.03370-23. Epub 2024 Jan 23. PMID: 38259066; PMCID: PMC10865811.
    50. Pratt CJ, Meili CH, Youssef NH, Hoback WW. Culture-independent analyses of carrion beetle (Coleoptera: Silphidae) secretion bacterial communities. Microbiol Spectr. 2023 Dec 12;11(6):e0169423. doi: 10.1128/spectrum.01694-23. Epub 2023 Oct 24. PMID: 37874151; PMCID: PMC10714842.
    51. Jones AL, Clayborn J, Pribil E, Foote AP, Montogomery D, Elshahed MS, Youssef NH. Temporal progression of anaerobic fungal communities in dairy calves from birth to maturity. Environ Microbiol. 2023 Nov;25(11):2088-2101. doi: 10.1111/1462-2920.16443. Epub 2023 Jun 12. PMID: 37305988.
    52. Mulay SA, Alexander WG, Hahn CR, Klingeman DM, Elshahed MS, Youssef NH, Podar M. Complete Genome Sequence of Desulfomicrobium Strain ZS1 from Zodletone Spring in Oklahoma, USA. Microbiol Resour Announc. 2023 May 17;12(5):e0014523. doi: 10.1128/mra.00145-23. Epub 2023 Apr 13. PMID: 37052391; PMCID: PMC10190684.
    53. Pratt CJ, Chandler EE, Youssef NH, Elshahed MS. Testudinimyces gracilis nov, sp. nov. and Astrotestudinimyces divisusgen. nov, sp. nov., two novel, deep-branching anaerobic gut fungal genera from tortoise faeces. Int J Syst Evol Microbiol. 2023 May;73(5). doi: 10.1099/ijsem.0.005921. PMID: 37252853.
    54. Meili CH, TagElDein MA, Jones AL, Moon CD, Andrews C, Kirk MR, Janssen PH, J Yeoman C, Grace S, Borgogna J-LC, Foote AP, Nagy YI, Kashef MT, Yassin AS, Elshahed MS, Youssef NH. Diversity and community structure of anaerobic gut fungi in the rumen of wild and domesticated herbivores. Appl Environ Microbiol. 2024 Feb 21;90(2):e0149223. doi: 10.1128/aem.01492-23. Epub 2024 Feb 1. PMID: 38299813; PMCID: PMC10880628.
    55. N-dihydrogalactochitosan serves as an effective mucosal adjuvant for intranasal vaccine in combination with recombinant viral proteins against respiratory infection. Ashley R Hoover, Sunil More, Kaili Liu, Connor L West, Trisha I Valerio, Coline L Furrer, Jacob P Adams, Ningli Yu, Crystal Villalva, Amit Kumar, Lu Alleruzzo, Samuel SK Lam, Tomas Hode, James F Papin, Wei R Chen. Acta Biomaterialia Volume 175, February 2024, Pages 279-292
    56. SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice. Yousef M Alhammad, Srivatsan Parthasarathy, Roshan Ghimire , Joseph J O'Connor, Catherine M Kerr, Jessica J Pfannenstiel, Debarati Chanda, Caden A Miller, Rob Unckless, Sonia Zuniga, Luis Enjuanes , Sunil More , Rudragouda Channappanavar , and Anthony Fehr. August 22, 2023, 120 (35) e2302083120
    57. Chanda, D.; Del Rivero, T.; Ghimire, R.; More, S.; Mitrani, M.I.; Bellio, M.A.; Channappanavar, R. Acellular Human Amniotic Fluid-Derived Extracellular Vesicles as Novel Anti-Inflammatory Therapeutics against SARS-CoV-2 Infection. Viruses 2024, 16, 273. https://doi.org/10.3390/v16020273
    58. SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice. Yousef M Alhammad, Srivatsan Parthasarathy, Roshan Ghimire , Joseph J O'Connor, Catherine M Kerr, Jessica J Pfannenstiel, Debarati Chanda, Caden A Miller, Rob Unckless, Sonia Zuniga, Luis Enjuanes , Sunil More , Rudragouda Channappanavar , and Anthony Fehr. PNAS, August 22, 2023, 120 (35) e2302083120.
  • Core Directors/Mentors
    1. Chiaranunt P, Burrows K, Ngai L, Tai SL, Cao EY, Liang H, Hamidzada H, Wong A, Gschwend J, Flüchter P, Kuypers M, Despot T, Momen A, Lim SM, Mallevaey T, Schneider C, Conway T, Imamura H, Epelman S, Mortha A. Microbial energy metabolism fuels an intestinal macrophage niche in solitary isolated lymphoid tissues through purinergic signaling. Sci Immunol. 2023 Aug 4;8(86):eabq4573. doi: 10.1126/sciimmunol.abq4573. Epub 2023 Aug 4. PMID: 37540734.
    2. Doranga S, Conway T. OmpC-Dependent Bile Tolerance Contributes to E. coli Colonization of the Mammalian Intestine. Microbiol Spectr. 2023 Jun 15;11(3):e0524122. doi: 10.1128/spectrum.05241-22. Epub 2023 Apr 4. PMID: 37014216; PMCID: PMC10269588.
    3. Doranga S, Conway T. Nitrogen assimilation by  coliin the mammalian intestine. mBio. 2024 Feb 21:e0002524. doi: 10.1128/mbio.00025-24. Epub ahead of print. PMID: 38380942.
    4. Righi C, Franzoni G, Feliziani F, Jones C, Petrini S. The Cell-Mediated Immune Response against Bovine alphaherpesvirus 1 (BoHV-1) Infection and Vaccination. Vaccines (Basel). 2023 Apr 2;11(4):785. doi: 10.3390/vaccines11040785. PMID: 37112697; PMCID: PMC10144493.
    5. Santos VC, Ostler JB, Harrison KS, Jones C. Slug, a Stress-Induced Transcription Factor, Stimulates Herpes Simplex Virus 1 Replication and Transactivates a cis-Regulatory Module within the VP16 Promoter. J Virol. 2023 Apr 27;97(4):e0007323. doi: 10.1128/jvi.00073-23. Epub 2023 Apr 6. PMID: 37022165; PMCID: PMC10134811.
    6. Jones C. Intimate Relationship Between Stress and Human Alpha‑Herpes Virus 1 (HSV‑1) Reactivation from Latency. Curr Clin Microbiol Rep. 2023 Dec;10(4):236-245. doi: 10.1007/s40588-023-00202-9. Epub 2023 Jul 27. PMID: 38173564; PMCID: PMC10764003.
    7. Harrison KS, Wijesekera N, Robinson AGJ, Santos VC, Oakley RH, Cidlowski JA, Jones C. Impaired glucocorticoid receptor function attenuates herpes simplex virus 1 production during explant-induced reactivation from latency in female mice. J Virol. 2023 Oct 31;97(10):e0130523. doi: 10.1128/jvi.01305-23. Epub 2023 Oct 12. PMID: 37823644; PMCID: PMC10617412.
    8. El-Mayet FS, Jones C. Specificity protein 1 (Sp1) and glucocorticoid receptor (GR) stimulate bovine alphaherpesvirus 1 (BoHV-1) replication and cooperatively transactivate the immediate early transcription unit 1 promoter. J Virol. 2024 Jan 23;98(1):e0143623. doi: 10.1128/jvi.01436-23. Epub 2023 Dec 12. PMID: 38084958; PMCID: PMC10804982.
    9. Isola JVV, Ocañas SR, Hubbart CR, Ko S, Mondal SA, Hense JD, Carter HNC, Schneider A, Kovats S, Alberola-Ila J, Freeman WM, Stout MB. A single-cell atlas of the aging murine ovary. bioRxiv [Preprint]. 2023 Sep 6:2023.04.29.538828. doi: 10.1101/2023.04.29.538828. Update in: Nat Aging. 2024 Jan;4(1):145-162. PMID: 37162983; PMCID: PMC10168416.
    10. Isola JVV, Ocañas SR, Hubbart CR, Ko S, Mondal SA, Hense JD, Carter HNC, Schneider A, Kovats S, Alberola-Ila J, Freeman WM, Stout MB. A single-cell atlas of the aging mouse ovary. Nat Aging. 2024 Jan;4(1):145-162. doi: 10.1038/s43587-023-00552-5. Epub 2024 Jan 10. PMID: 38200272; PMCID: PMC10798902.
    11. Schafer CM, Martin-Almedina S, Kurylowicz K, Dufton N, Osuna-Almagro L, Wu ML, Johnson CF, Shah AV, Haskard DO, Buxton A, Willis E, Wheeler K, Turner S, Chlebicz M, Scott RP, Kovats S, Cleuren A, Birdsey GM, Randi AM, Griffin CT. Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory Challenge. Arterioscler Thromb Vasc Biol. 2023 Aug;43(8):1412-1428. doi: 10.1161/ATVBAHA.123.318926. Epub 2023 Jun 15. PMID: 37317853; PMCID: PMC10364964.
    12. Miller RAJ, Williams AP, Kovats S. Sex chromosome complement and sex steroid signaling underlie sex differences in immunity to respiratory virus infection. Front Pharmacol. 2023 Mar 30;14:1150282. doi: 10.3389/fphar.2023.1150282. PMID: 37063266; PMCID: PMC10097973.
    13. Roe MM, Do T, Turner S, Jevitt AM, Chlebicz M, White K, Oomens AGP, Rankin S, Kovats S, Gappa-Fahlenkamp H. Blood myeloid cells differentiate to lung resident cells and respond to pathogen stimuli in a 3D human tissue-engineered lung model. Front Bioeng Biotechnol. 2023 Jul 7;11:1212230. doi: 10.3389/fbioe.2023.1212230. PMID: 37485324; PMCID: PMC10361305.
    14. Surendran A, Huang C, Liu L. Circular RNAs and their roles in idiopathic pulmonary fibrosis. Respir Res. 2024 Feb 6;25(1):77. doi: 10.1186/s12931-024-02716-2. PMID: 38321530; PMCID: PMC10848557.
    15. Guthrie CM, Tan X, Meeker AC, Self AE, Liu L, Cheng Y. Engineering a dual vaccine against COVID-19 and tuberculosis. Front Cell Infect Microbiol. 2023 Oct 26;13:1273019. doi: 10.3389/fcimb.2023.1273019. PMID: 37965265; PMCID: PMC10641007.
    16. Zhu Z, Yang X, Huang C, Liu L. The Interferon-Induced Protein with Tetratricopeptide Repeats Repress Influenza Virus Infection by Inhibiting Viral RNA Synthesis. Viruses. 2023 Jun 22;15(7):1412. doi: 10.3390/v15071412. PMID: 37515100; PMCID: PMC10384122.
    17. Vaddadi K, Gandikota C, Huang C, Liang Y, Liu L. Cellular microRNAs target SARS-CoV-2 spike protein and restrict viral replication. Am J Physiol Cell Physiol. 2023 Aug 1;325(2):C420-C428. doi: 10.1152/ajpcell.00516.2022. Epub 2023 Jul 3. PMID: 37399496; PMCID: PMC10390048.
    18. Cliburn KD, Kemp PM, Huestis MA, Wagner JR, Payton M, Liu L, Liang Y, Maxwell LK. Time- and temperature-dependent postmortem ∆9-tetrahydrocannabinol concentration changes in rabbits following controlled inhaled cannabis administration. J Anal Toxicol. 2023 Dec 12;47(9):850-857. doi: 10.1093/jat/bkad076. PMID: 37758448.
    19. Vermeire CA, Tan X, Liang Y, Kotey SK, Rogers J, Hartson SD, Liu L, Cheng Y. Mycobacterium abscessus extracellular vesicles increase mycobacterial resistance to clarithromycin in vitro. Proteomics. 2024 Jan 18:e2300332. doi: 10.1002/pmic.202300332. Epub ahead of print. PMID: 38238893.
    20. Pushparaj, S., Gandikota, C., Vaddadi, K., Liang Y., and Liu, L. (2023) SNHG15 aids SARS-CoV-2 entry via RABL2A. RNA Biol. 20, 539-547. PMCID: PMC10399485
    21. Bamunuarachchi, G., Vaddadi, K., Yang, X., Dang, Q., Zhu, Z., Hewawasam, S., Huang, C., Liang, Y., Guo, Y., and Liu, L. (2023) MicroRNA-9-1 Attenuates Influenza A Virus Replication via Targeting Tankyrase 1. J. innate Immun. 15: 647-664., PMCID: PMC10601686
    22. Wu W, Zhang W, Alexandar JS, Booth JL, Miller CA, Xu C, Metcalf JP. RIG-I agonist SLR10 promotes macrophage M1 polarization during influenza virus infection. Front Immunol. 2023 Jul 5;14:1177624. doi: 10.3389/fimmu.2023.1177624. PMID: 37475869; PMCID: PMC10354434.
    23. Ozonoff A, Jayavelu ND, Liu S, Melamed E, Milliren CE, Qi J, Geng LN, McComsey GA, Cairns CB, Baden LR, Schaenman J, Shaw AC, Samaha H, Seyfert-Margolis V, Krammer F, Rosen LB, Steen H, Syphurs C, Dandekar R, Shannon CP, Sekaly RP, Ehrlich LIR, Corry DB, Kheradmand F, Atkinson MA, Brakenridge SC, Higuita NIA, Metcalf JP, Hough CL, Messer WB, Pulendran B, Nadeau KC, Davis MM, Sesma AF, Simon V, van Bakel H, Kim-Schulze S, Hafler DA, Levy O, Kraft M, Bime C, Haddad EK, Calfee CS, Erle DJ, Langelier CR, Eckalbar W, Bosinger SE; IMPACC Network; Peters B, Kleinstein SH, Reed EF, Augustine AD, Diray-Arce J, Maecker HT, Altman MC, Montgomery RR, Becker PM, Rouphael N. Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study. Nat Commun. 2024 Jan 3;15(1):216. doi: 10.1038/s41467-023-44090-5. PMID: 38172101; PMCID: PMC10764789.
    24. Gygi JP, Maguire C, Patel RK, Shinde P, Konstorum A, Shannon CP, Xu L, Hoch A, Jayavelu ND, Network I, Haddad EK, Reed EF, Kraft M, McComsey GA, Metcalf J, Ozonoff A, Esserman D, Cairns CB, Rouphael N, Bosinger SE, Kim-Schulze S, Krammer F, Rosen LB, van Bakel H, Wilson M, Eckalbar W, Maecker H, Langelier CR, Steen H, Altman MC, Montgomery RR, Levy O, Melamed E, Pulendran B, Diray-Arce J, Smolen KK, Fragiadakis GK, Becker PM, Augustine AD, Sekaly RP, Ehrlich LIR, Fourati S, Peters B, Kleinstein SH, Guan L. Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants. bioRxiv [Preprint]. 2023 Nov 6:2023.11.03.565292. doi: 10.1101/2023.11.03.565292. PMID: 37986828; PMCID: PMC10659275.
    25. Ozonoff A, Schaenman J, Jayavelu ND, Milliren CE, Calfee CS, Cairns CB, Kraft M, Baden LR, Shaw AC, Krammer F, van Bakel H, Esserman DA, Liu S, Sesma AF, Simon V, Hafler DA, Montgomery RR, Kleinstein SH, Levy O, Bime C, Haddad EK, Erle DJ, Pulendran B, Nadeau KC, Davis MM, Hough CL, Messer WB, Agudelo Higuita NI, Metcalf JP, Atkinson MA, Brakenridge SC, Corry D, Kheradmand F, Ehrlich LIR, Melamed E, McComsey GA, Sekaly R, Diray-Arce J, Peters B, Augustine AD, Reed EF, Altman MC, Becker PM, Rouphael N; IMPACC Study Group Members. Corrigendum to "Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: results from the IMPACC study" [eBioMedicine 83 (2022) 104208]. EBioMedicine. 2023 Dec;98:104860. doi: 10.1016/j.ebiom.2023.104860. Epub 2023 Nov 1. Erratum for: EBioMedicine. 2022 Sep;83:104208. PMID: 37918220; PMCID: PMC10643088.
    26. Holter DL, Nafe LA, Dugat DR, Hallman M, Ritchey JW, Fielder S, Rudra P. Diagnostic utility of ultrasound-guided fine-needle aspiration and needle-core biopsy sampling of canine splenic masses. Can J Vet Res. 2023 Oct;87(4):265-271. PMID: 37790262; PMCID: PMC10542949.
    27. Gilliam LL, Gilliam J, Samuel SP, Carter RW, Ritchey J, Bulfone T, Gutiérrez JM, Williams DJ, Durkin DM, Stephens SI, Lewin MR. Oral and IV Varespladib Rescue Experiments in Juvenile Pigs with Weakness Induced by Australian and Papuan Oxyuranus scutellatus Toxins (Basel). 2023 Sep 7;15(9):557. doi: 10.3390/toxins15090557. PMID: 37755983; PMCID: PMC10537020.
    28. Vicosa Bauermann F, Falkenberg S, Rudd JM, Peter CM, Merchioratto I, Ritchey JW, Gilliam J, Taylor J, Ma H, Maggioli MF. Immune Responses to Influenza D Virus in Calves Previously Infected with Bovine Viral Diarrhea Virus 2. Viruses. 2023 Dec 16;15(12):2442. doi: 10.3390/v15122442. PMID: 38140683; PMCID: PMC10747992.
    29. Xu S, Mo D, Rizvi FZ, Rosa JP, Ruiz J, Tan S, Tweten RK, Leong JM, Adams W. Pore-forming activity of  pneumoniaepneumolysin disrupts the paracellular localization of the epithelial adherens junction protein E-cadherin. Infect Immun. 2023 Sep 14;91(9):e0021323. doi: 10.1128/iai.00213-23. Epub 2023 Aug 21. PMID: 37607057; PMCID: PMC10501216.
  • Center Investigators
    1. Gyawali S, Tirumala RTA, Loh H, Andiappan M, Bristow AD. Photocarrier Recombination Dynamics in Highly Scattering Cu2O Nanocatalyst Clusters. J Phys Chem C Nanomater Interfaces. 2024 Jan 24;128(5):2003-2011. doi: 10.1021/acs.jpcc.3c06941. PMID: 38352855; PMCID: PMC10860136.
    2. Eeda V, Patil NY, Joshi AD, Awasthi V. Advancements in metabolic-associated steatotic liver disease research: Diagnostics, small molecule developments, and future directions. Hepatol Res. 2023 Dec 27. doi: 10.1111/hepr.14008. Epub ahead of print. PMID: 38149861.
    3. Sciarrillo CM, Short KR, Keirns BH, Elliott DC, Clarke SL, Palle S, Emerson SR. Postprandial triglycerides and fibroblast growth factor 19 as potential screening tools for paediatric non-alcoholic fatty liver disease. Pediatr Obes. 2023 Apr;18(4):e13007. doi: 10.1111/ijpo.13007. Epub 2023 Feb 3. PMID: 36734693.
    4. Harris MS, Dolan RF, Bryce JR, Ewusi JG, Cook GA. In Vitro Glycosylation of the Membrane Protein γ-Sarcoglycan in Nanodiscs. ACS Omega. 2023 Oct 20;8(43):40904-40910. doi: 10.1021/acsomega.3c06135. PMID: 37929139; PMCID: PMC10620887.
    5. Stover MA, Tinoco-Bravo B, Shults CA, Marouk S, Deole R, Manjarrez JR. Probiotic effects of Lactococcus lactisand Leuconostoc mesenteroides on stress and longevity in Caenorhabditis elegans. Front Physiol. 2023 Sep 12;14:1207705. doi: 10.3389/fphys.2023.1207705. PMID: 37772058; PMCID: PMC10522913.
    6. Dey A, Pramanik PK, Dwivedi SKD, Neizer-Ashun F, Kiss T, Ganguly A, Rice H, Mukherjee P, Xu C, Ahmad M, Csiszar A, Bhattacharya R. A role for the cystathionine-β-synthase /H2S axis in astrocyte dysfunction in the aging brain. Redox Biol. 2023 Dec;68:102958. doi: 10.1016/j.redox.2023.102958. Epub 2023 Nov 6. PMID: 37948927; PMCID: PMC10663824.
    7. Li Y, Xiao P, Boadu F, Goldkamp AK, Nirgude S, Cheng J, Hagen DE, Kalish JM, Rivera RM. The counterpart congenital overgrowth syndromes Beckwith-Wiedemann Syndrome in human and large offspring syndrome in bovine involve alterations in DNA methylation, transcription, and chromatin configuration. medRxiv [Preprint]. 2023 Dec 16:2023.12.14.23299981. doi: 10.1101/2023.12.14.23299981. PMID: 38168424; PMCID: PMC10760283.
    8. Goldkamp AK, Lahuis CH, Hagen DE, Taxis TM. Influence of Maternal BLV Infection on miRNA and tRF Expression in Calves. Pathogens. 2023 Nov 3;12(11):1312. doi: 10.3390/pathogens12111312. PMID: 38003777; PMCID: PMC10674961.
    9. Goldkamp AK, Hagen DE. Implications of tRNA abundance on translation elongation across bovine tissues. Front Genet. 2023 Dec 19;14:1308048. doi: 10.3389/fgene.2023.1308048. PMID: 38174049; PMCID: PMC10763252.
    10. Triant DA, Walsh AT, Hartley GA, Petry B, Stegemiller MR, Nelson BM, McKendrick MM, Fuller EP, Cockett NE, Koltes JE, McKay SD, Green JA, Murdoch BM, Hagen DE, Elsik CG. AgAnimalGenomes: browsers for viewing and manually annotating farm animal genomes. Mamm Genome. 2023 Sep;34(3):418-436. doi: 10.1007/s00335-023-10008-1. Epub 2023 Jul 17. PMID: 37460664; PMCID: PMC10382368.
    11. Tuggle CK, Clarke JL, Murdoch BM, Lyons E, Scott NM, Beneš B, Campbell JD, Chung H, Daigle CL, Das Choudhury S, Dekkers JCM, Dórea JRR, Ertl DS, Feldman M, Fragomeni BO, Fulton JE, Guadagno CR, Hagen DE, Hess AS, Kramer LM, Lawrence-Dill CJ, Lipka AE, Lübberstedt T, McCarthy FM, McKay SD, Murray SC, Riggs PK, Rowan TN, Sheehan MJ, Steibel JP, Thompson AM, Thornton KJ, Van Tassell CP, Schnable PS. Current challenges and future of agricultural genomes to phenomes in the USA. Genome Biol. 2024 Jan 3;25(1):8. doi: 10.1186/s13059-023-03155-w. PMID: 38172911; PMCID: PMC10763150.
    12. Nilsson JB, Kaabinejadian S, Yari H, Peters B, Barra C, Gragert L, Hildebrand W, Nielsen M. Machine learning reveals limited contribution of trans-only encoded variants to the HLA-DQ immunopeptidome. Commun Biol. 2023 Apr 21;6(1):442. doi: 10.1038/s42003-023-04749-7. PMID: 37085710; PMCID: PMC10121683.
    13. Feng Y, Hess PR, Tompkins SM, Hildebrand WH, Zhao S. A Kmer-based paired-end readde novoassembler and genotyper for canine MHC class I genotyping. iScience. 2023 Jan 16;26(2):105996. doi: 10.1016/j.isci.2023.105996. PMID: 36798440; PMCID: PMC9926114.
    14. Krawic JR, Ladd NA, Cansler M, McMurtrey C, Devereaux J, Worley A, Ahmed T, Froyd C, Kulicke CA, Swarbrick G, Nilsen A, Lewinsohn DM, Adams EJ, Hildebrand W. Multiple Isomers of Photolumazine V Bind MR1 and Differentially Activate MAIT Cells. J Immunol. 2024 Jan 26:ji2300609. doi: 10.4049/jimmunol.2300609. Epub ahead of print. PMID: 38275935.
    15. Nilsson JB, Kaabinejadian S, Yari H, Kester MGD, van Balen P, Hildebrand WH, Nielsen M. Accurate prediction of HLA class II antigen presentation across all loci using tailored data acquisition and refined machine learning. Sci Adv. 2023 Nov 24;9(47):eadj6367. doi: 10.1126/sciadv.adj6367. Epub 2023 Nov 24. PMID: 38000035; PMCID: PMC10672173.
    16. Knoche SM, Larson AC, Brumfield GL, Cate S, Hildebrand WH, Solheim JC. Correction: Major histocompatibility complex class I molecule expression by pancreatic cancer cells is regulated by activation and inhibition of the epidermal growth factor receptor. Immunol Res. 2023 Dec 5. doi: 10.1007/s12026-023-09442-9. Epub ahead of print. Erratum for: Immunol Res. 2022 Jun;70(3):371-391. PMID: 38051459.
    17. Kulicke CA, Swarbrick GM, Ladd NA, Cansler M, Null M, Worley A, Lemon C, Ahmed T, Bennett J, Lust TN, Heisler CM, Huber ME, Krawic JR, Ankley LM, McBride SK, Tafesse FG, Olive AJ, Hildebrand WH, Lewinsohn DA, Adams EJ, Lewinsohn DM, Harriff MJ. Delivery of loaded MR1 monomer results in efficient ligand exchange to host MR1 and subsequent MR1T cell activation. Commun Biol. 2024 Feb 24;7(1):228. doi: 10.1038/s42003-024-05912-4. PMID: 38402309; PMCID: PMC10894271.
    18. Zhang M, Chen C, Lu Z, Cai Y, Li Y, Zhang F, Liu Y, Chen S, Zhang H, Yang S, Gen H, Jiang Y, Ning C, Huang J, Wang W, Fan L, Zhang Y, Jin M, Han J, Xiong Z, Cai M, Liu J, Huang C, Yang X, Xu B, Li H, Li B, Zhu X, Wei Y, Zhu Y, Tian J, Miao X. Genetic Control of Alternative Splicing and its Distinct Role in Colorectal Cancer Mechanisms. Gastroenterology. 2023 Nov;165(5):1151-1167. doi: 10.1053/j.gastro.2023.07.019. Epub 2023 Aug 3. PMID: 37541527.
    19. Ying P, Chen C, Lu Z, Chen S, Zhang M, Cai Y, Zhang F, Huang J, Fan L, Ning C, Li Y, Wang W, Geng H, Liu Y, Tian W, Yang Z, Liu J, Huang C, Yang X, Xu B, Li H, Zhu X, Li N, Li B, Wei Y, Zhu Y, Tian J, Miao X. Genome-wide enhancer-gene regulatory maps link causal variants to target genes underlying human cancer risk. Nat Commun. 2023 Sep 25;14(1):5958. doi: 10.1038/s41467-023-41690-z. PMID: 37749132; PMCID: PMC10520073.
    20. Liang P, Zhang J, Wu Y, Zheng S, Xu Z, Yang S, Wang J, Ma S, Xiao L, Hu T, Jiang W, Huang C, Xing Q, Kundu M, Wang B. An ULK1/2-PXN mechanotransduction pathway suppresses breast cancer cell migration. EMBO Rep. 2023 Nov 6;24(11):e56850. doi: 10.15252/embr.202356850. Epub 2023 Oct 17. PMID: 37846507; PMCID: PMC10626438.
    21. Li B, Cai Y, Chen C, Li G, Zhang M, Lu Z, Zhang F, Huang J, Fan L, Ning C, Li Y, Wang W, Geng H, Liu Y, Chen S, Li H, Yang S, Zhang H, Tian W, Zhu Z, Xu B, Li H, Li H, Jin M, Wang X, Zhang S, Liu J, Huang C, Yang X, Wei Y, Zhu Y, Tian J, Miao X. Genetic Variants That Impact Alternative Polyadenylation in Cancer Represent Candidate Causal Risk Loci. Cancer Res. 2023 Nov 1;83(21):3650-3666. doi: 10.1158/0008-5472.CAN-23-0251. PMID: 37669142.
    22. Surendran A, Huang C, Liu L. Circular RNAs and their roles in idiopathic pulmonary fibrosis. Respir Res. 2024 Feb 6;25(1):77. doi: 10.1186/s12931-024-02716-2. PMID: 38321530; PMCID: PMC10848557.
    23. Fan L, Cai Y, Wang H, Zhang H, Chen C, Zhang M, Lu Z, Li Y, Zhang F, Ning C, Wang W, Liu Y, Li H, Li G, Peng J, Hu K, Li B, Huang C, Yang X, Wei Y, Zhu Y, Jin M, Miao X, Tian J. Saturated fatty acid intake, genetic risk and colorectal cancer incidence: A large-scale prospective cohort study. Int J Cancer. 2023 Aug 1;153(3):499-511. doi: 10.1002/ijc.34544. Epub 2023 Apr 23. PMID: 37087737.
    24. Huang C, Luo Y, Zeng B, Chen Y, Liu Y, Chen W, Liao X, Liu Y, Wang Y, Wang X. Branched-chain amino acids prevent obesity by inhibiting the cell cycle in an NADPH-FTO-m6A coordinated manner. J Nutr Biochem. 2023 Dec;122:109437. doi: 10.1016/j.jnutbio.2023.109437. Epub 2023 Sep 2. PMID: 37666478.
    25. Zou D, Cai Y, Jin M, Zhang M, Liu Y, Chen S, Yang S, Zhang H, Zhu X, Huang C, Zhu Y, Miao X, Wei Y, Yang X, Tian J. A genetic variant in the immune-related gene ERAP1 affects colorectal cancer prognosis. Chin Med J (Engl). 2024 Feb 20;137(4):431-440. doi: 10.1097/CM9.0000000000002845. Epub 2023 Sep 8. PMID: 37690994; PMCID: PMC10876254.
    26. Lu Z, Fan L, Zhang F, Huang C, Cai Y, Chen C, Li G, Zhang M, Huang J, Ning C, Li Y, Wang W, Geng H, Liu Y, Chen S, Li H, Yang S, Zhang H, Tian W, Ye T, Liu J, Yang X, Xu B, Zhu Y, Zhong R, Li H, Tian J, Li B, Miao X. HSPA12A was identified as a key driver in colorectal cancer GWAS loci 10q26.12 and modulated by an enhancer-promoter interaction. Arch Toxicol. 2023 Jul;97(7):2015-2028. doi: 10.1007/s00204-023-03494-4. Epub 2023 May 28. PMID: 37245169.
    27. Gong JJ, Huang IH, Su MS, Xie SX, Liu WY, Huang CR, Hung YP, Wu SR, Tsai PJ, Ko WC, Chen JW. Phage transcriptional regulator X (PtrX)-mediated augmentation of toxin production and virulence in Clostridioides difficile strain R20291. Microbiol Res. 2024 Mar;280:127576. doi: 10.1016/j.micres.2023.127576. Epub 2023 Dec 22. PMID: 38183754.’
    28. Szabo S, Zayachkivska O, Hussain A, Muller V. What is really 'Long COVID'? Inflammopharmacology. 2023 Apr;31(2):551-557. doi: 10.1007/s10787-023-01194-0. Epub 2023 Mar 25. PMID: 36964860; PMCID: PMC10039447.
    29. Hussain A, Shrewsbury RP, Mattingly A, Draugalis JR, Nutan MT, Nazzal S, Islam MA. Compounding Education in US PharmD Curricula. Am J Pharm Educ. 2023 Oct;87(10):100117. doi: 10.1016/j.ajpe.2023.100117. Epub 2023 May 24. PMID: 37852686.
    30. Susek KH, Schwietzer YA, Karvouni M, Gilljam M, Keszei M, Hussain A, Lund J, Kashif M, Lundqvist A, Ljunggren HG, Nahi H, Wagner AK, Alici E. Generation of NK cells with chimeric-switch receptors to overcome PD1-mediated inhibition in cancer immunotherapy. Cancer Immunol Immunother. 2023 May;72(5):1153-1167. doi: 10.1007/s00262-022-03317-y. Epub 2022 Nov 10. PMID: 36355079; PMCID: PMC10110653.
    31. Karvouni M, Vidal-Manrique M, Susek KH, Hussain A, Gilljam M, Zhang Y, Gray JD, Lund J, Kaufmann G, Ljunggren HG, Ji H, Lundqvist A, Wagner AK, Guo W, Alici E. Challenges in αCD38-chimeric antigen receptor (CAR)-expressing natural killer (NK) cell-based immunotherapy in multiple myeloma: Harnessing the CD38dim phenotype of cytokine-stimulated NK cells as a strategy to prevent fratricide. Cytotherapy. 2023 Jul;25(7):763-772. doi: 10.1016/j.jcyt.2023.03.006. Epub 2023 Apr 11. PMID: 37055320.
    32. Asghar N, Hussain A, Nguyen DA, Ali S, Hussain I, Junejo A, Ali A. Advancement in nanomaterials for environmental pollutants remediation: a systematic review on bibliometrics analysis, material types, synthesis pathways, and related mechanisms. J Nanobiotechnology. 2024 Jan 10;22(1):26. doi: 10.1186/s12951-023-02151-3. PMID: 38200605; PMCID: PMC10777661.
    33. Cho HY, Wang X, Campbell MR, Panduri V, Coviello S, Caballero MT, Bennett BD, Kleeberger SR, Polack FP, Ofman G, Bell DA. Prospective epigenome and transcriptome analyses of cord and peripheral blood from preterm infants at risk of bronchopulmonary dysplasia. Sci Rep. 2023 Jul 28;13(1):12262. doi: 10.1038/s41598-023-39313-0. PMID: 37507442; PMCID: PMC10382533.
    34. Villalva C, Patil G, Narayanan S, Chanda D, Ghimire R, Snider T, Ramachandran A, Channappanavar R, More S. Klebsiella pneumoniae Co-infection Leads to Fatal Pneumonia in SARS-CoV-2-infected Mice. bioRxiv [Preprint]. 2023 Aug 1:2023.07.28.551035. doi: 10.1101/2023.07.28.551035. PMID: 37577517; PMCID: PMC10418095.
    35. Chandrasekar N, Sharma K, Jain S, Shinde M, Patil G, Shah RP. A critical assessment on stability behaviour of Vorinostat using LC-MS-QTOF with H/D exchange and NMR. J Pharm Biomed Anal. 2023 Nov 30;236:115687. doi: 10.1016/j.jpba.2023.115687. Epub 2023 Aug 28. PMID: 37657178.
    36. Parate SK, Vura S, Pal S, Khandelwal U, Sandilya Ventrapragada RS, Rai RK, Molleti SH, Kumar V, Patil G, Jain M, Mallya A, Ahmadi M, Kooi B, Avasthi S, Ranjan R, Raghavan S, Chandorkar S, Nukala P. Giant electrostriction-like response from defective non-ferroelectric epitaxial BaTiO3integrated on Si (100). Nat Commun. 2024 Feb 16;15(1):1428. doi: 10.1038/s41467-024-45903-x. PMID: 38365898; PMCID: PMC10873356.
    37. Wouters CL, Heydarian N, Pusavat J, Panlilio H, Lam AK, Moen EL, Brennan RE, Rice CV. Breaking membrane barriers to neutralize E. coli and K. pneumoniae virulence with PEGylated branched polyethylenimine. Biochim Biophys Acta Biomembr. 2023 Aug;1865(6):184172. doi: 10.1016/j.bbamem.2023.184172. Epub 2023 May 17. PMID: 37201561; PMCID: PMC10330601.
    38. Raguraman R, Bhavsar D, Kim D, Ren X, Sikavitsas V, Munshi A, Ramesh R. Tumor-targeted exosomes for delivery of anticancer drugs. Cancer Lett. 2023 Apr 1;558:216093. doi: 10.1016/j.canlet.2023.216093. Epub 2023 Feb 21. PMID: 36822543; PMCID: PMC10025995.
    39. Burrows K, Figueroa-Hall L, Stewart J, Alarbi A, Kuplicki R, Hannafon B, Tan C, Risbrough V, McKinney B, Ramesh R, Victor T, Aupperle R, Savitz J, Teague K, Khalsa S, Paulus M. Exploring the role of neuronal-enriched extracellular vesicle miR-93 and interoception in major depressive disorder. Res Sq [Preprint]. 2023 Jun 16:rs.3.rs-2813878. doi: 10.21203/rs.3.rs-2813878/v1. PMID: 37398092; PMCID: PMC10312986.
    40. Kang C, Ren X, Lee D, Ramesh R, Nimmo S, Yang-Hartwich Y, Kim D. Harnessing small extracellular vesicles for pro-oxidant delivery: novel approach for drug-sensitive and resistant cancer therapy. J Control Release. 2024 Jan;365:286-300. doi: 10.1016/j.jconrel.2023.11.031. Epub 2023 Nov 25. PMID: 37992875; PMCID: PMC10872719.
    41. Ceballos-Santa MC, Sierra A, Zalbidea IM, Lazarus E, Marin-Montealegre V, Ramesh S, Iglesias P, Wuertz-Kozak K, Rivero IV. Aloe vera-based biomaterial ink for 3D bioprinting of wound dressing constructs. J Biomed Mater Res B Appl Biomater. 2024 Feb;112(2):e35379. doi: 10.1002/jbm.b.35379. PMID: 38348505.
    42. Vicosa Bauermann F, Falkenberg S, Rudd JM, Peter CM, Merchioratto I, Ritchey JW, Gilliam J, Taylor J, Ma H, Maggioli MF. Immune Responses to Influenza D Virus in Calves Previously Infected with Bovine Viral Diarrhea Virus 2. Viruses. 2023 Dec 16;15(12):2442. doi: 10.3390/v15122442. PMID: 38140683; PMCID: PMC10747992.
    43. Rochowski MT, Jayathilake K, Balcerak JM, Selvan MT, Gunasekara S, Miller C, Rudd JM, Lacombe VA. Impact of Delta SARS-CoV-2 Infection on Glucose Metabolism: Insights on Host Metabolism and Virus Crosstalk in a Feline Model. Viruses. 2024 Feb 15;16(2):295. doi: 10.3390/v16020295. PMID: 38400070; PMCID: PMC10893195.
    44. Villalva C, Patil G, Narayanan S, Chanda D, Ghimire R, Snider T, Ramachandran A, Channappanavar R, More S. Klebsiella pneumoniae Co-infection Leads to Fatal Pneumonia in SARS-CoV-2-infected Mice. bioRxiv [Preprint]. 2023 Aug 1:2023.07.28.551035. doi: 10.1101/2023.07.28.551035. PMID: 37577517; PMCID: PMC10418095.
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